Results 31 to 40 of about 164,361 (137)
Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
Weimar, Charlotte H. E. +29 more
core +2 more sources
Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
HLA-G MOLECULES: FROM EMBRYO IMPLANTATION TO OOCYTE MATURATION [PDF]
Background Assisted reproduction technique (ART) pregnancy rates have not changed in recent years and an increased risk of twins, triplets or higher order pregnancies leads to a perinatal mortality and morbidity.
Rizzo, Roberta
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Mast Cells in Nonmammalian Vertebrates. An Overview
"Mast cells are best known as multifunctional entities that may confer a benefit. on immune system. This review presents the known facts on mast-cell system. and breakthroughs in mast-cell biology in fish, amphibians, reptiles, and birds.. As compared to
Claudia Pinelli +9 more
core +1 more source
Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos +3 more
wiley +1 more source
We assessed the impact of pregnancy on cognition and cell proliferation in the live‐bearing fish Poeciliopsis gracilis. Pregnant females showed reduced spatial learning but unchanged reversal learning, alongside decreased cell proliferation in the olfactory bulb and ventral telencephalon, indicating pregnancy‐induced cognitive and neural changes in a ...
Tiffany R. Ernst +7 more
wiley +1 more source
Histone Density and Dynamics Shape Mitotic Chromatid Architecture in Xenopus Egg Extracts
Histone chaperones and chromatin remodelers modulate histone density and dynamics. The resulting local chromatin properties are integrated with DNA reconfiguration activities mediated by condensins and topoisomerase IIα to shape the global architecture of mitotic chromosomes.
Keishi Shintomi +3 more
wiley +1 more source
Optimizing embryo culture conditions and spent culture media analysis as predictors of embryo quality and pregnancy [PDF]
Philosophiae Doctor - PhDThe aim of this thesis is first, to evaluate various culture conditions to improve embryo development, and secondly, to analyze spent culture media for any biomarkers that may be predictive of embryo health.
Kaskar, Khalied
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Dopaminergic neurons are particularly susceptible to ferroptosis. Pacemaking activity–driven calcium (Ca2+) influx increases metabolic demand and reactive oxygen species (ROS) production, promoting iron release from aconitase. Alpha‐synuclein (α‐syn) enhances iron uptake via transferrin receptor 1 (TfR1) and exhibits ferrireductase activity, converting
Carmem L. Sperlich +2 more
wiley +1 more source
Coordination of Hox identity between germ layers along the anterior-to-posterior axis of the vertebrate embryo [PDF]
During early embryonic development, a relatively undifferentiated mass of cells is shaped into a complex and morphologically differentiated embryo. This is achieved by a series of coordinated cell movements that end up in the formation of the three ...
Lloret Vilaspasa, F.
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