Results 21 to 30 of about 9,662 (120)

EE2 and the Fish Brain: Age‐Dependent Impact of 17α‐Ethinylestradiol on Brain Cell Proliferation and Behavior in Sea Bass Larvae

Environmental Toxicology, EarlyView.
ABSTRACT Endocrine‐disrupting chemicals (EDCs), such as 17α‐ethinylestradiol (EE2), have raised concerns about their potential effects on aquatic organisms, particularly during early developmental stages. In this context, the study of behavioral disruption has gained considerable attention, as it may have consequences on individual fitness and ...
Soloperto Sofia, Stephanie Olivier, Céline Thomasse, Christophe Minier, Marie‐Pierre Halm‐Lemeille, Christelle Jozet‐Alves, Salima Aroua   +6 more
wiley   +1 more source

Exposure of zebrafish to brominated environmental chemicals [PDF]

, 2010
Fish reproduction and embryonic development may be sensitive to environmental chemicals. This thesis investigated effects of brominated flame retardants (BFRs) and polybrominated dibenzo-p-dioxins (PBDDs) on reproduction and early life-stage development ...
Norman Haldén, Anna
core  

Egg activation at fertilization by a soluble sperm protein

, 2016
The most fundamental unresolved issue of fertilization is to define how the sperm activates the egg to begin embryo development. Egg activation at fertilization in all species thus far examined is caused by some form of transient increase in the ...
Swann, Karl, Lai, Francis Anthony
core   +1 more source

KU80 suppresses endonuclease G activity to preserve genomic integrity

The FEBS Journal, EarlyView.
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan, Kwang‐Hyun Park, Hae Ryung Chang, Eunyoung Jung, Myung‐Jin Kim, Jeeyoon Kang, Hyunjo Shim, Eui‐Jeon Woo, Yonghwan Kim   +8 more
wiley   +1 more source

An evolutionarily conserved program of B-cell development and activation in zebrafish.

, 2013
Teleost fish are among the most ancient vertebrates possessing an adaptive immune system with B and T lymphocytes that produce memory responses to pathogens.
Pao, Yvonne, Chi, Neil C, Pratt, David N, Yang, Hongbo, Jacobsen, Bradley H, Page, Dawne M, Bertrand, Julien, Lewis, Kanako L, McGue, Caitlyn, Wittamer, Valérie, Delgado, Noemi, Schale, Sarah E, Magor, Brad G, Traver, David, Bertrand, Julien Y, Doty, Alyssa   +15 more
core   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source

The Impacts of Pregnancy on Cognition and Cell Proliferation in a Live‐Bearing Fish (Poeciliopsis gracilis)

European Journal of Neuroscience, Volume 63, Issue 9, May 2026.
We assessed the impact of pregnancy on cognition and cell proliferation in the live‐bearing fish Poeciliopsis gracilis. Pregnant females showed reduced spatial learning but unchanged reversal learning, alongside decreased cell proliferation in the olfactory bulb and ventral telencephalon, indicating pregnancy‐induced cognitive and neural changes in a ...
Tiffany R. Ernst, Alianne Keijzer, Sofia Vellere, Anthony Lee, Johan L. van Leeuwen, Alexander Kotrschal, Aniko Korosi, Bart J. A. Pollux   +7 more
wiley   +1 more source

Determination and stability of gonadal sex

, 2010
The discovery that the SRY gene induces male sex in humans and other mammals led to speculation about a possible equivalent for female sex. But females are proving to be more complicated.
Uda, Manuela, Pelosi, Emanuele, Garcia-Ortiz, José-Elias, Crisponi, Laura, Schlessinger, David, Forabosco, Antonino   +5 more
core   +1 more source

Histone Density and Dynamics Shape Mitotic Chromatid Architecture in Xenopus Egg Extracts

Genes to Cells, Volume 31, Issue 3, May 2026.
Histone chaperones and chromatin remodelers modulate histone density and dynamics. The resulting local chromatin properties are integrated with DNA reconfiguration activities mediated by condensins and topoisomerase IIα to shape the global architecture of mitotic chromosomes.
Keishi Shintomi, Keita Ohsumi, Mari Iwabuchi, Tatsuya Hirano   +3 more
wiley   +1 more source

Caenorhabditis elegans chromatin-associated proteins SET-2 and ASH-2 are differentially required for histone H3 Lys 4 methylation in embryos and adult germ cells

, 2011
Methylation of histone H3 lysine 4 (H3K4me), a mark associated with gene activation, is mediated by SET1 and the related mixed lineage leukemia (MLL) histone methyltransferases (HMTs) across species.
Korswagen, H.C., Robert, Valérie, Korswagen, H., Rakotomalala, C., Strome, S., Cécile Bedet, Strome, Susan, Soete, Gwen, Robert, V. J., Korswagen, Hendrik C., Robert, V.J., Robert, V., Dunkelbarger, Steve, Susan Strome, Simonet, T., Gwen Soete, Palladino, F., Rakotomalala, Cédric, Valérie J. P. Robert, Xiao, Yu, Xiao, Y., Palladino, Francesca, Soete, G., Bedet, Cécile, Hendrik C. Korswagen, Thomas Simonet, Steve Dunkelbarger, Simonet, Thomas, Francesca Palladino, Bedet, C., Dunkelbarger, S., Cédric Rakotomalala, Yu Xiao   +32 more
core   +1 more source