Results 51 to 60 of about 164,361 (137)

The Interplay of Ontogeny and Phylogeny at the Transcriptome Level of the Tetrapod Heart

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 6, Page 325-340, September 2025.
The main stages of development during which species‐specific heart anatomy is determined in the ontogeny of representative tetrapods. Transcriptomic similarity is expected earlier in development before heart anatomy diverges. ABSTRACT The tetrapod heart is characterized by three chambers in amphibians and non‐avian reptiles, as opposed to four in birds,
G. A. Cordero   +10 more
wiley   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

Enigmatic Nodal and Lefty gene repertoire discrepancy: Latent evolutionary history revealed by vertebrate‐wide phylogeny

open access: yesDevelopmental Dynamics, Volume 254, Issue 8, Page 887-901, August 2025.
Abstract Homology in vertebrate body plans is traditionally ascribed to the high‐level conservation of regulatory components within the genetic programs governing them, particularly during the “phylotypic stage.” However, advancements in embryology and molecular phylogeny have unveiled the dynamic nature of gene repertoires responsible for early ...
Shigehiro Kuraku
wiley   +1 more source

Embryo-mediated genome editing for accelerated genetic improvement of livestock

open access: yes, 2021
Selecting beneficial DNA variants is the main goal of animal breeding. However, this process is inherently inefficient because each animal only carries a fraction of all desirable variants. Genome editing technology with its ability to directly introduce
Zachariah McLean (15402779)   +2 more
core  

Arguing Along the Slippery Slope of Human Embryo Research

open access: yes, 1996
One frequent argument in the debate over federal funding of human embryo research is the slippery slope argument. Slope arguments can be of several types: either logical, empirical, or full (a combination of logical and empirical slope arguments, with an
Freeman, Jeanne Salmon
core   +1 more source

Embryonic stem cells: modelling effects ofearly embryo environment

open access: yes, 2013
The Developmental Origins of Health and Disease (DOHaD) hypothesis proposes that embryonic environment can induce permanent changes in metabolism during development, increasing the risk of disease in adults. Adverse environments during critical stages of
Cox, Andrew
core   +1 more source

Micro-magnetic resonance imaging study of live quail embryos during embryonic development [PDF]

open access: yes, 2011
Eggs containing live Japanese quail embryos were imaged using micro-magnetic resonance imaging (μMRI) at 24-h intervals from Day 0 to 8, the period during which the main body axis is being laid down and organogenesis is taking place.
Welten, Monique   +14 more
core   +1 more source

Blood Flow and The Mammalian Embryo [PDF]

open access: yes, 2005
Hemodynamics, or blood fluid dynamics, is of great importance in vascular biology and its role is well recognized in events ranging from atherosclerosis to wound healing.
Jones, Elizabeth Anne Vincent
core   +1 more source

The Spare Embryo: A Red Herring in the Embryo Experimentation Debate

open access: yes, 1993
Whenever embryo experimentation is discussed the question of whether it is preferable to use spare or specifically produced ('research') embryos for destructive embryo experimentation always enters the debate at some stage.
Holm, Soren
core   +1 more source

Embryo Research: The Ethical Geography of the Debate

open access: yes, 1997
Three basic political positions on embryo research will be identified as libertarian, conservative, and social-democratic. The Human Embryo Research Panel will be regarded as an expression of the social-democratic position.
Khushf, George
core   +1 more source

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