Results 21 to 30 of about 773,120 (317)
Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors
A role for Slit/Robo signalling in pancreas development has not been defined. Here, the authors generate Robo1/Robo2 knockout mice to identify both as needed for establishing initial pancreatic cell identity as well as for proliferation and survival of ...
Sophie Escot +4 more
doaj +1 more source
Epigenetic regulation of germ cell and early embryonic development by Polycomb group proteins [PDF]
Mammalian development begins at fertilization, when two highly specialized gametes, sperm and oocyte fuse to form a zygote. It is well established that early development of the embryo is driven by factors that are inherited from the oocyte.
Pósfai, Eszter
core +1 more source
Objective: The present study was aimed to identify hub genes associated with recurrent spontaneous abortion (RSA) via both bioinformatics analysis and clinical verification, also to evaluate the related pathways and immune infiltration situation of RSA ...
Yun-Xi Chen +3 more
doaj +1 more source
Mechanobiology of Embryonic Limb Development [PDF]
Abstract: Considerable evidence exists to support the hypothesis that mechanical forces have an essential role in healthy embryonic skeletal development. Clinical observations and experimental data indicate the importance of muscle contractions for limb development.
Prendergast, Patrick +2 more
openaire +4 more sources
Molecular mechanisms separating two axonal pathways during embryonic development of the avian optic tectum [PDF]
During embryonic development of the avian optic tectum, retinal and tectobulbar axons form an orthogonal array of nerve processes. Growing axons of both tracts are transiently very closely apposed to each other. Despite this spatial proximity, axons from
Kröger, Stephan +3 more
core +1 more source
Ho-Bouldoires, Sollier, Zamfirov and Broders-Bondon et al. show that high frequency pulsatile mechanical stresses maintain the physiological level of mice colon stem cells through the mechanosensitive Ret kinase and that Ret activation is elevated in ...
Thanh Huong Nguyen Ho-Bouldoires +18 more
doaj +1 more source
Signalling Pathways in Embryonic Development [PDF]
The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate ...
Stricker, Sigmar +2 more
core +1 more source
Developmental potential of aneuploid human embryos cultured beyond implantation
Aneuploidy, abnormal chromosome number, is a major cause of early pregnancy loss. Here the authors determine the extent of post-implantation development of human embryos with common aneuploidies in culture, finding developmental arrest of monosomy 21 ...
Marta N. Shahbazi +11 more
doaj +1 more source
Liver and pancreas cells arise from a common endoderm progenitor in the embryo, but what regulates their cell fate is unclear. Here, the authors show that expression of the Three-Amino-acid-Loop-Extension (TALE) homeobox TG-interacting factor 2 (TGIF2 ...
Nuria Cerdá-Esteban +9 more
doaj +1 more source
Regulation of the maternal-to-embryonic transition in "C. elegans" [PDF]
Reproduction is a fundamental process of life which allows the survival of each species through the birth of young species members. Several modes of reproduction evolved and are classified into sexual and asexual reproduction.
Finger, Susanne
core +1 more source

