Results 31 to 40 of about 773,120 (317)

Stage-specific histone modification profiles reveal global transitions in the Xenopus embryonic epigenome. [PDF]

, 2011
Vertebrate embryos are derived from a transitory pool of pluripotent cells. By the process of embryonic induction, these precursor cells are assigned to specific fates and differentiation programs.
Jose M. Arteaga-Salas, Edith Mentele, Ralph A. W. Rupp, Arteaga-Salas, Jose M., Tobias D Schneider, Schneider, Tobias D., Tobias D. Schneider, Rupp, Ralph A. W., Jose M Arteaga-Salas, Ralph A W Rupp, Imhof, Axel, Nicetto, Dario, Dario Nicetto, Robert David, Axel Imhof, Mentele, Edith, David, Robert   +16 more
core   +1 more source

Notch promotes neural lineage entry by pluripotent embryonic stem cells [PDF]

, 2006
A central challenge in embryonic stem (ES) cell biology is to understand how to impose direction on primary lineage commitment. In basal culture conditions, the majority of ES cells convert asynchronously into neural cells.
Smith, Austin G, Austin G Smith, Heavey Barry, Alexandra Benchoua, Benchoua, Alexandra, Smith, Austin,, Benchoua Alexandra, Sally Lowell, Smith Austin G, Lowell, Sally; id_orcid, Smith, Austin, G., Lowell Sally, Lowell, Sally, Heavey, Barry, Barry Heavey   +14 more
core   +1 more source

Effect of a commercial rice pesticide on embryonic and larval development of climbing perch (Anabas testudineus) [PDF]

, 2019
Pesticides are chemicals that are used to kill pests, including insects, rodents and fungi. Pesticides are very toxic to other organisms, including humans, animals and environments. This research was aimed to examine the effect of a commercial brand rice
Rosman, Farah Nurasyikin, Mohamed Zulperi, Zarirah   +1 more
core   +1 more source

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]

, 2011
The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Glenda J. Dickson, Pamela M. Corrigan, Freeburn, R.W., Robin W. Freeburn, Dickson, Glenda, Thompson, Alexander, Ramsey, Joanne, Helen Wheadon, Wheadon, H., Dickson, G.J., Edwina Dobbin, Alexander Thompson, Ramsey, J.M., Corrigan, P.M., Joanne M. Ramsey, Dobbin, E., Thompson, A.   +16 more
core   +1 more source

Transcription factor OTX2 silences the expression of cleavage embryo genes and transposable elements

The Journal of Reproduction and Development, 2021
Upon mammalian fertilization, zygotic genome activation (ZGA) and activation of transposable elements (TEs) occur in early embryos to establish totipotency and support embryogenesis.
Shi-meng GUO, Ning-hua MEI, Jing YANG, Li-quan ZHOU   +3 more
doaj   +1 more source

Embryonic development of Pachycheles chubutensis (Decapoda: Anomura) [PDF]

, 2009
The different stages of embryonic development of the porcellanid crab Pachycheles chubutensis are described, along with the chronology of each stage at 16±1°C.
Dupré, Enrique, Gonzalez Pisani, Ximena, Rubilar Panasiuk, Cynthia Tamara   +2 more
core   +1 more source

Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis

BMC Medicine, 2023
Background Pre-eclampsia (PE) is one of the leading causes of maternal and fetal morbidity/mortality during pregnancy, and alpha-2-macroglobulin (A2M) is associated with inflammatory signaling; however, the pathophysiological mechanism by which A2M is ...
Jingyun Wang, Ping Zhang, Mengyuan Liu, Zhengrui Huang, Xiaofeng Yang, Yuzhen Ding, Jia Liu, Xin Cheng, Shujie Xu, Meiyao He, Fengxiang Zhang, Guang Wang, Ruiman Li, Xuesong Yang   +13 more
doaj   +1 more source

Utilizing Playdoh in the Classroom to Construct a 3D Model Depicting Cellular Movements and Tissue Remodeling during Human Gastrulation, Early Organogenesis, and Embryonic Folding

Journal of Microbiology & Biology Education, 2021
In classroom studies of mammalian embryology, students must fully grasp the cellular and tissue remodeling needed to initiate gastrulation to ensure comprehension of forthcoming developmental processes such as tissue specification and organogenesis ...
Ryan Hesterman, Shannon Rose, Will LeFever, Ryan Stewart, Martina Krone, Camryn Holihan, Kristin Ackerman   +6 more
doaj   +1 more source

Genomic instability in individuals with sex determination defects and germ cell cancer

Cell Death Discovery, 2023
The ability to transmit genetic information through generations depends on the preservation of genome integrity. Genetic abnormalities affect cell differentiation, causing tissue specification defects and cancer.
Maria Krivega, Jutta Zimmer, Anna Slezko, Petra Frank-Herrmann, Julia Rehnitz, Markus Hohenfellner, Markus Bettendorf, Marcin Luzarowski, Thomas Strowitzki   +8 more
doaj   +1 more source

ID3 mediates BMP2-induced downregulation of ICAM1 expression in human endometiral stromal cells and decidual cells

Frontiers in Cell and Developmental Biology, 2023
Recurrent pregnancy loss (RPL) remains an unsolved problem in obstetrics and gynecology, and up to 50% of RPL cases are unexplained. Unexplained RPL (uRPL) is widely considered to be related to an aberrant endometrial microenvironment.
Jin Luo, Jin Luo, Yaqin Wang, Hsun-Ming Chang, Hua Zhu, Jing Yang, Peter C. K. Leung   +6 more
doaj   +1 more source