Results 281 to 290 of about 573,263 (362)

Differentiation of the mononuclear phagocyte system during mouse embryogenesis:the role of transcription factor PU.1 [PDF]

, 1999
Browne, C M, Henkel, G W, Hume, D A, Lichanska, A M, Maki, R A, McKercher, S R, Murphy, K M, Ostrowski, M C   +7 more
core  

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

IRE1α RNase activity is critical for early embryo development by degrading maternal transcripts. [PDF]

Nucleic Acids Res
Li C, Tan YP, Gao D, Su R, Xu K, Liu SC, Li XF, Lu YH, Yi LT, Wang G, Ou XH, Meng TG, Sun QY.   +12 more
europepmc   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Maternal diet-induced alterations in uterine fluid sncRNAs compromise preimplantation embryo development and offspring metabolic health. [PDF]

Nat Commun
Pan S, Zhang L, Yang X, Wang L, Liu C, Zhang J, Yu X, Qiao S, Zeng R, Qian Y, Tong L, Liu X, Shi J, Yan L, Zhang Y.   +14 more
europepmc   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Progestin-only pretreatment enhances follicular synchronization and embryo development: a three-arm retrospective cohort study in GnRH antagonist cycles. [PDF]

Contracept Reprod Med
Kobanawa M.
europepmc   +1 more source

SMC2 ablation impairs bovine embryo development shortly after blastocyst hatching

Alba Pérez-Gómez, Inés Flores-Borobia, Julieta Gabriela Hamze, Beatriz Galiano-Cogolludo, Ismael Lamas‐Toranzo, Leopoldo González‐Brusi, Priscila Ramos‐Ibeas, Pablo Bermejo‐Álvarez   +7 more
openalex   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Regulation of HvASN1 expression by bZIP transcription factors during barley embryo development and germination. [PDF]

Planta
Contreras E, Alonso R, Pastor-Mora E, Ceballos MG, Vicente-Carbajosa J, Iglesias-Fernández R.   +5 more
europepmc   +1 more source