Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin +14 more
wiley +1 more source
Regulation of the Homeostasis of Early Embryo Development in Dairy Cows by Targeted Editing of the <i>PRLR</i> Gene-Mediated Activation of the Anti-Heat Stress Pathway. [PDF]
Cheng X +6 more
europepmc +1 more source
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
Impact of paternal high energy diets on semen quality and embryo development in cattle. [PDF]
Fontes PLP +3 more
europepmc +1 more source
c-Abl Plays an Important Role in Mouse Preimplantation Embryo Development and the Dysregulation Associated With Decreased mTERT Expression. [PDF]
Yildirim E, Onel T, Yaba A.
europepmc +1 more source
Sustained in-ovo and in-feed probiotic supplementation promotes embryo development and post-hatch performance in broilers. [PDF]
Ren Y +8 more
europepmc +1 more source
Zinc eluted from glassware is a risk factor for embryo development in human and animal assisted reproduction†. [PDF]
Yao T +17 more
europepmc +1 more source
Evaluation of Lysophosphatidic Acid Effects and Its Receptors During Bovine Embryo Development. [PDF]
Yu B +5 more
europepmc +1 more source

