Results 141 to 150 of about 6,903,993 (298)

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Prognostic Role of Pronuclear Morphology as a Marker of Embryo Quality

Medical Journal of Babylon
Background: Selection of transferred embryos for assisted reproduction required special care. Scoring of the morphological features for 18, 44, and 68 h after intracytoplasmic sperm injection.
Hind Abdulkadim, Ban J. Edan, Muhjah Falah Hassan   +2 more
doaj   +1 more source

A Comprehensive Comparison of PICSI and ICSI Techniques Through a Triple-Blinded Trial: Effects on Embryo Quality, Cumulative Pregnancy Rate, and Live Birth Rate

Biomedicines
Background: Sperm selection is critical in assisted reproduction, typically relying on swim-up and centrifugation density gradients. New methods, such as PICSI (physiological intracytoplasmic sperm selection), aim to enhance outcomes by selecting mature ...
Lucia Alegre, Laura Carrión-Sisternas, Lorena Bori, Irene Hervás, Jose Remohí, Nicolás Garrido, Marcos Meseguer   +6 more
doaj   +1 more source

Embryo oxygen consumption to evaluate the embryo quality [PDF]

Fertility and Sterility, 2018
A. Fukui, R. Takeyama, Y. Wakimoto, Y. Ukita, H. Shibahara   +4 more
openaire   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

Effects of Temperature on Reproductive Performance and Embryo Quality of Female Eriocheir sinensis

Progress in Fishery Sciences
The Chinese mitten crab (Eriocheir sinensis) is an economically important species in China, and its reproductive performance and embryo quality are particularly important for the quality of newly hatched larvae. E.
Chaoyue CUI, Zhi GENG, Guangpeng FENG, Tao ZHANG, Feng ZHAO, Gang YANG, Ping ZHUANG, Xiaorong HUANG   +7 more
doaj   +1 more source

Engineered Nanotopography to Modulate Growth and Signaling of Neuronal Networks

Advanced Functional Materials, EarlyView.
This study examines the interaction between neurons and nanoscale topographies on engineered substrates. Neurons cultured on nanowires, nanopillars and nanoneedles exhibit enhanced neurite outgrowth, form more organized neuronal circuits, and display improved synaptic connectivity, compared to flat substrates.
Hao Nguyen Tran, Kalyan Shobhana, Zlatan Trifunovic, Dan Smith, Michael Stuiber, Chennupati Jagadish, Mirella Dottori, Andrea J. O'Connor, Vini Gautam   +8 more
wiley   +1 more source

Large-Scale Embryo Transfer Operation in Dromedary Camels: Retrospective Analysis of the Association Between Key Clinical Factors and the 2-Month Pregnancy Rate

Animals
ET is used in camel reproduction to increase the reproductive potential of elite females selected for production and show. This retrospective study analyzed the association between factors related to embryo flushing (flushing fluid turbidity and debris),
Taher Kamal Osman, Sayed Taha Ismail, Hossam R. El-Sherbiny   +2 more
doaj   +1 more source

Non-Invasive Testing of Embryo Quality

, 2015
Full text is available to authenticated members of The University of Auckland only.Infertility is a growing medical concern in New Zealand and around the world, and is often treated using IVF and other assisted reproductive technologies. Selection of the
Rout, Milly
core  

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source