Results 81 to 90 of about 7,472,763 (290)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Comparison of Time Lapse Embryo Morphokinetics Monitoring and Conventional Pronuclear Morphology Assessment to Determine Embryo Quality in Endometriosis Patients [PDF]

, 2016
ObjectiveEndometriosis patients who underwent IVF program has poorer embryo quality, leads to low successive rate. In order to determine embryo quality, time lapse embryo monitoring and pronuclear (PN) morphology assessment were used to predict and ...
Emeraldi, Malvin, Muharam, R., Ikhsan, Muhammad, Wiweko, Budi, Setiyawan, Wisnu   +4 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Mitochondrial DNA copy number level in the culture medium of human embryos as a factor in predicting the onset and prolongation of pregnancy

RUDN Journal of Medicine
Relevance. A key factor influencing the effectiveness of assisted reproductive technology programmes is the quality of the embryo transferred into the uterine cavity.
Olga I. Lisitsyna, Nataliya P. Makarova, Aleksey M. Krasnyi, Alexey N. Ekimov, Andrey Yu. Romanov, Nataliya V. Dolgushina   +5 more
doaj   +1 more source

Effect of endometrial thickness and embryo quality on live-birth rate of fresh IVF/ICSI cycles: a retrospective cohort study

Reproductive Biology and Endocrinology, 2020
Background Successful implantation and delivery require both the functional embryo and receptive endometrium in assisted reproductive technology (ART) cycles. However, little is known about embryo-endometrial interaction on live-birth.
Hong Lv, Xiuzhu Li, Jiangbo Du, Xiufeng Ling, Feiyang Diao, Qun Lu, Shiyao Tao, Lei Huang, Shiyao Chen, Xiumei Han, Kun Zhou, Bo Xu, Xiaoyu Liu, Hongxia Ma, Yankai Xia, Hongbing Shen, Zhibin Hu, Guangfu Jin, Yichun Guan, Xinru Wang   +19 more
doaj   +1 more source

Relationship between embryo quality and aneuploidies

Reproductive BioMedicine Online, 2006
Many high-grade embryos selected for transfer according to their morphological evaluation were detected to have chromosomal abnormalities after aneuploidy screening for infertility by preimplantation genetic diagnosis (PGD). The aim of this study was to detect if there is any correlation between embryo quality and genetic status. The chromosomal status
V, Baltaci, H, Satiroglu, C, Kabukçu, E, Unsal, B, Aydinuraz, O, Uner, Y, Aktas, E, Cetinkaya, F, Turhan, A, Aktan   +9 more
openaire   +2 more sources

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Concentration of stromal cell‐derived factor‐1 (SDF‐1/CXCL12) in the follicular fluid is associated with blastocyst development

Reproductive Medicine and Biology, 2019
Purpose To study the association between stromal cell‐derived factor‐1 (SDF‐1/CXCL12) and vascular endothelial growth factor (VEGF) concentrations in individual human ovarian follicles and IVF outcomes.
Akemi Nishigaki, Tomoko Tsuzuki‐Nakao, Takeharu Kido, Naoko Kida, Maiko Kakita‐Kobayashi, Hiromi Murata, Hidetaka Okada   +6 more
doaj   +1 more source

Top‐quality embryo transfer is associated with lower odds of ectopic pregnancy

Acta Obstetricia et Gynecologica Scandinavica, 2022
Introduction The incidence of ectopic pregnancy is up to four times higher after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) than in spontaneous pregnancies, and the risk of ectopic pregnancy is increased by tubal factor ...
Simona Anzhel, Sirpa Mäkinen, Helena Tinkanen, Tiina Mikkilä, Anni Haltia, Antti Perheentupa, Candido Tomás, Hannu Martikainen, Aila Tiitinen, Juha S. Tapanainen, Zdravka Veleva   +10 more
doaj   +1 more source

Contribution of JAM-1 to epithelial differentiation and tight-junction biogenesis in the mouse preimplantation embryo [PDF]

, 2004
We have investigated the contribution of the tight junction (TJ) transmembrane protein junction-adhesion-molecule 1 (JAM-1) to trophectoderm epithelial differentiation in the mouse embryo.
Fay C. Thomas, Dejana, E., Bhavwanti Sheth, Tom P. Fleming, Fleming, T.P., Sheth, B., Judith J. Eckert, Gianfranco Bazzoni, Elisabetta Dejana, Bazzoni, G., Thomas, F.C., Eckert, J.J.   +11 more
core   +1 more source