Results 31 to 40 of about 279,297 (287)

Integrative Single-Cell Transcriptomic Analysis of Human Fetal Thymocyte Development

Frontiers in Genetics, 2021
Intrathymic differentiation of T lymphocytes begins as early as intrauterine stage, yet the T cell lineage decisions of human fetal thymocytes at different gestational ages are not currently understood. Here, we performed integrative single-cell analyses
Yuchen Li, Yuchen Li, Yuchen Li, Weihong Zeng, Weihong Zeng, Weihong Zeng, Tong Li, Tong Li, Tong Li, Yanyan Guo, Yanyan Guo, Yanyan Guo, Guangyong Zheng, Xiaoying He, Xiaoying He, Lilian Bai, Lilian Bai, Lilian Bai, Guolian Ding, Guolian Ding, Guolian Ding, Li Jin, Li Jin, Xinmei Liu, Xinmei Liu, Xinmei Liu   +25 more
doaj   +1 more source

Human Stem Cell-Based Embryo Models in Implantation Research: Regulation, Consistency and Potential

Biomolecules
The use of human stem cell-based embryo models (hSCBEM) in implantation research is developing rapidly. This raises regulatory and ethical issues as these models become more complex and get closer to morphological and functional identity with human ...
Søren Holm
doaj   +1 more source

Cloned buffalo bulls and their somatic cell donor bulls exhibit similar in-vitro embryo production efficienc

Revista Científica, 2023
Somatic cell nuclear transfer (SCNT) has emerged as a valuable assisted reproductive technology for faster multiplication of animals. This helps to preserve the valuable superior germplasm.
Tanya Gupta, Gaurav Tripathi, Sonal Gupta, Naresh L. Selokar, Manoj Kumar Singh   +4 more
doaj  

Prostaglandin F2α (PGF2α) production possibility and its receptors expression in the early- and late-cleaved preimplantation bovine embryos

BMC Veterinary Research, 2019
Background Prostaglandin F2α (PGF2α) is an important component for the physiology of female reproductive processes. In the literature, the data pertaining to the synthesis and action of PGF2α in early embryonic bovine development are limited.
Katarzyna Grycmacher, Dorota Boruszewska, Emilia Sinderewicz, Ilona Kowalczyk-Zięba, Joanna Staszkiewicz-Chodor, Izabela Woclawek-Potocka   +5 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Comparative Proteomic Analysis of Young and Adult Bull (Bos taurus) Cryopreserved Semen

Animals, 2021
The age of the bull is widely accepted to influence the production of sperm, affecting the amount and quality of produced semen, which in turn impacts the results of cryopreservation.
Błażej Westfalewicz, Mariola Słowińska, Sylwia Judycka, Andrzej Ciereszko, Mariola A. Dietrich   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Long noncoding RNAs: new insights in modulating mammalian spermatogenesis

Journal of Animal Science and Biotechnology, 2020
Spermatogenesis is a complex differentiating developmental process in which undifferentiated spermatogonial germ cells differentiate into spermatocytes, spermatids, and finally, to mature spermatozoa.
Bahlibi Weldegebriall Sahlu, Shanjiang Zhao, Xiuge Wang, Saqib Umer, Huiying Zou, Jinming Huang, Huabin Zhu   +6 more
doaj   +1 more source