Results 51 to 60 of about 313,115 (285)

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

EMBRYO RESEARCH IN PLURALISTIC EUROPE [PDF]

, 2003
Introduction -- Summary -- Zusammenfassung -- Empfehlungen - - Ch. 1. Theoretical and practical possibilities in human embryo experimentation -- 1.1 The human problem -- 1.1.1 Infertility -- 1.1.2 Embryo loss -- 1.2 Experiments designed ...
Solter, D.; Beyleveld, D.; Friele, M.B.; Holowka, J.; Lilie, H.; Lovell-Badge, R.; Mandla, C.; Martin, U.; and Pardo Avellaneda, R.
core  

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

PAPERS COMMISSIONED FOR THE HUMAN EMBRYO RESEARCH PANEL, VOLUME II [PDF]

, 1994
Contains the following papers: THE HISTORY, CURRENT STATUS AND FUTURE DIRECTION OF RESEARCH INVOLVING HUMAN EMBRYOS, by Jonathan Van Blerkom; ETHICAL ISSUES IN HUMAN EMBRYO RESEARCH, by Bonnie Steinbock; CROSS-CULTURAL ANALYSIS OF POLICIES REGARDING ...
National Institutes of Health [NIH] (United States). Ad Hoc Group of Consultants to the Advisory Committee to the Director
core  

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

New insights into posttranslational modifications of proteins during bull sperm capacitation

Cell Communication and Signaling, 2023
Background Due to the unique nature of spermatozoa, which are transcriptionally and translationally silent, the regulation of capacitation is based on the formation of posttranslational modifications of proteins (PTMs).
Agnieszka Mostek-Majewska, Anna Majewska, Anna Janta, Andrzej Ciereszko   +3 more
doaj   +1 more source

Integrative Single-Cell Transcriptomic Analysis of Human Fetal Thymocyte Development

Frontiers in Genetics, 2021
Intrathymic differentiation of T lymphocytes begins as early as intrauterine stage, yet the T cell lineage decisions of human fetal thymocytes at different gestational ages are not currently understood. Here, we performed integrative single-cell analyses
Yuchen Li, Yuchen Li, Yuchen Li, Weihong Zeng, Weihong Zeng, Weihong Zeng, Tong Li, Tong Li, Tong Li, Yanyan Guo, Yanyan Guo, Yanyan Guo, Guangyong Zheng, Xiaoying He, Xiaoying He, Lilian Bai, Lilian Bai, Lilian Bai, Guolian Ding, Guolian Ding, Guolian Ding, Li Jin, Li Jin, Xinmei Liu, Xinmei Liu, Xinmei Liu   +25 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Comparative Expression Analysis of HSP70, HSP90, IL-4, TNF, KITLG and KIT-receptor Gene between Varicocele-Induced and Non-Varicocele Testes of Dog [PDF]

International Journal of Fertility and Sterility, 2017
Background This study was designed to create an experimental varicocele model by a simple surgical procedure in dog with minimum invasion and to investigate the effect of varicocele-induced infertility on the expression of six related genes (HSP90, HSP70,
Hossein Hassanpour, Amin Bigham Sadegh, Iraj Karimi, Heidar Heidari Khoei, Azarnoush Karimi, Parinaz Edalati Shaarbaf, Tahereh Karimi Shayan   +6 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source