Results 71 to 80 of about 313,115 (285)

The potential of the human embryo [PDF]

open access: yes, 2007
A higher order potential analysis of moral status clarifies the issues that divide Human Being Theorists who oppose embryo research from Person Theorists who favor embryo research.
Brown, Mark T.
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The embryo in relationships: a French debate on stem cell research [PDF]

open access: yes, 2004
While many European countries are entering unknown legal terrain where the embryo in vitro is concerned, France can already look back on a long tradition of public discussion and legal codification of ways of dealing with in vitro embryos.
Maio, Giovanni
core  

Media Supplementation With Gamma‐Oryzanol Improves the Outcome of Ovine Oocyte Maturation In Vitro

open access: yesVeterinary Medicine and Science
Background The process of maturing ovine oocyte in vitro has not yet been raised with acceptable results. Objective This study was designed to evaluate the γ‐oryzanol effect as a supplement of maturation media on the development of ovine oocytes to ...
Saeed Musapoor   +4 more
doaj   +1 more source

The effect of chemical treatment of the sheep embryo zona pellucida on the ability of blastocysts to hatch after vitrification and warming

open access: yesVeterinary Medicine and Science, 2022
Background The embryo release from the zona pellucida is of prerequisites of successful implantation. Objectives Regarding the negative impact of embryo cryopreservation on the blastocysts hatchability, the aim of the present study was to investigate the
Fatemeh‐Sadat Mousavi   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

THE EFFECT OF OXYTOCIN, PROSTAGLANDIN F2 OR GNRH INJECTION ON FRESH AND FROZEN-THAWED SEMEN CHARACTERISTICS OF RAMS [PDF]

open access: yesAssiut Veterinary Medical Journal, 2013
The present study aimed to maximize the semen output from rams using oxytocin, prostaglandin F2α (PG F2α) or gondatrophin releasing hormone (GnRH) as well as to study the effects of these treatments on quality, freezability and antioxidant activity of ...
EL-BADRY D.A.   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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