Results 231 to 240 of about 241,682 (297)

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Analysis of clinical factors affecting pregnancy outcomes after embryo transfer in patients with intrauterine adhesions. [PDF]

Front Med (Lausanne)
Liu J, Chen H, Lin B, Wang C, Ban D, Zhong X, Sun H.   +6 more
europepmc   +1 more source

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

Impact of serum progesterone levels and rescue progesterone supplemental luteal support on pregnancy outcomes in frozen embryo transfer: a controlled trial. [PDF]

BMC Pregnancy Childbirth
Azizi Kutenaee M, Falah Khorsand S, Fesahat F, Vahedi Raad M, Afshar F, Salehi E.   +5 more
europepmc   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Single vs. double good-quality embryo transfer in fresh cleavage-stage cycles: a propensity score-matched analysis of efficacy and risks. [PDF]

J Ovarian Res
Dong CY, Wang X, Zhu MY, Geng HW, Shi MM, Zhang CL.   +5 more
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Evaluation of the functional role of corpus luteum cavity in recipient selection for bovine embryo transfer. [PDF]

Anim Biosci
Park J, Qamar AY, Lee W, Song K, Park M, Hong L, Bang S, Ro Y, Lee S, Kim M, Yi J, Cho J.   +11 more
europepmc   +1 more source

Cloning: Legal, Medical, Ethical and Social Issues: Hearing before the Subcommittee on Health and Environment of the Committee on Commerce, U.S. House of Representatives, February 12, 1998: The Written Testimony of Dianne N. Irving, M.A., Ph.D. [PDF]

, 1999
Irving, Dianne N.
core   +1 more source

Successful fertility-preserving management using systemic methotrexate and laparoscopic resection of intramural pregnancy following in vitro fertilization and embryo transfer: a case report. [PDF]

Case Rep Womens Health
Sato-Shimizu M, Tajima H, Takemoto S, Asada H.   +3 more
europepmc   +1 more source