Results 311 to 320 of about 3,660,127 (401)

Regulation of Human Cloning: Implication for Biotechnological Advancement [PDF]

, 2011
McDaniel, Michael J.
core   +2 more sources

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Why should we check the tubes in IVF patients with ovarian endometriosis before embryo transfer? a retrospective study. [PDF]

BMC Pregnancy Childbirth
Yazicioglu C, Yuceturk A, Karaosmanoglu O, Aslan IO, Peker N, Cakiroglu Y, Tiras B.   +6 more
europepmc   +1 more source

[Book Review of] \u3cem\u3eLaw and Ethics of A.I.D. and Embryo Transfer\u3c/em\u3e, Ciba Foundation Symposium J7 [PDF]

, 1974
Lebel, Robert Roger
core   +1 more source

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source

Analysis of factors influencing pregnancy and its outcomes in women undergoing in vitro fertilization-embryo transfer/frozen embryo transfer cycles: A retrospective study. [PDF]

Medicine (Baltimore)
Zhang H, Zhang YY, Cheng Y, Yan H, Zheng X.   +4 more
europepmc   +1 more source

Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations

Advanced Science, EarlyView.
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi, Mohamed Ramadan, Lu Yu, Fengjiao Hui, Amjad Hussain, Xiaofeng Zhou, Yu Yu, Xianlong Zhang, Shuangxia Jin   +8 more
wiley   +1 more source

Associations between inactivated COVID-19 vaccination status and timing and fertility and pregnancy outcomes following frozen-thawed embryo transfer: a prospective cohort study. [PDF]

Front Endocrinol (Lausanne)
Liu D, Chen L, Cai H, Zhou H, Wang M, Li N, Xue X, Tian L, Mol BW, Shi W, Shi J.   +10 more
europepmc   +1 more source

Synthetic Cells, Synthetic Life, and Inheritance [PDF]

, 2011
Knapland, Kristine S.
core   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source