Results 211 to 220 of about 68,692 (266)

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

Advanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long, Meng Wang, Ruolin Mao, Hong Chen, Juepu Zhou, Xiangfei Wang, Zheng Yuan, Ri‐Cheng Chian, Nan Xiao, Qingsong Xi, Yimin Shu, Lei Jin, Lixia Zhu   +12 more
wiley   +1 more source

Automated biomedical hypothesis generation with time-aware hypergraph contrastive learning. [PDF]

Knowl Inf Syst
Shariatmadari AH, Guo S, Sheffield NC, Zhang A, Jha K.   +4 more
europepmc   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

Protecting laboratory air quality and comparing clinical assisted reproductive technology cycle outcomes before, during and after wildfire events: a retrospective cohort study. [PDF]

Front Reprod Health
Ratnayaka-Gamage ND, Cao Y, Tran A, Rainczuk K, Stringer JM, Hutt KJ, Sorby K, Winship AL.   +7 more
europepmc   +1 more source

Congenital aphallia: From embryology to management - a focused minireview. [PDF]

World J Clin Pediatr
Nahid E, Ahmad MF, Shafique MA.
europepmc   +1 more source

ESHRE recommendations on Good Practice in the IVF laboratory†. [PDF]

Hum Reprod
ESHRE Good Practice in the IVF Lab Working Group , Arroyo G, Barrie A, Coticchio G, Ebner T, Kirkman-Brown J, Le Clef N, Lundin K, Magli C, Quesada Martinez M, de Los Santos Molina MJ, Tilleman K, Sfontouris I.   +12 more
europepmc   +1 more source

Editorial expression of concern (EEoC): Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts. [PDF]

BMC Cancer
Tsang CM, Cheung YC, Lui VW, Yip YL, Zhang G, Lin VW, Cheung KC, Feng Y, Tsao SW.   +8 more
europepmc   +1 more source

Doxorubicin and 4-Hydroperoxycyclophosphamide Alter Mitochondrial Dynamics and miR-34 Expression in Spermatogonia and Spermatocytes In Vitro. [PDF]

Basic Clin Pharmacol Toxicol
Öztatlıcı H, Özbilgin MK, Çolaksel RB, Saygılı SK, Öztatlıcı M.   +4 more
europepmc   +1 more source