Results 31 to 40 of about 481,310 (353)

Competence, specification and commitment to an olfactory placode fate [PDF]

, 2008
The nasal placode shares a common origin with other sensory placodes within a pre-placodal domain at the cranial neural plate border. However, little is known about early events in nasal placode development as it segregates from prospective lens, neural ...
Bhattacharyya, Sujata, Bronner-Fraser, Marianne   +1 more
core   +2 more sources

Self-contained induction of neurons from human embryonic stem cells. [PDF]

PLoS ONE, 2009
BACKGROUND: Neurons and glial cells can be efficiently induced from mouse embryonic stem (ES) cells in a conditioned medium collected from rat primary-cultured astrocytes (P-ACM).
Tsuyoshi Okuno, Takashi Nakayama, Nae Konishi, Hideo Michibata, Koji Wakimoto, Yutaka Suzuki, Shinji Nito, Toshio Inaba, Imaharu Nakano, Shin-Ichi Muramatsu, Makoto Takano, Yasushi Kondo, Nobuo Inoue   +12 more
doaj   +1 more source

OCT4B2, a novel alternative spliced variant of OCT4, is significantly upregulated under heat-stress condition and downregulated in differentiated cells

Tumor Biology, 2017
OCT4 is a crucial transcription factor that maintains self-renewal and pluripotency of embryonic stem and embryonic carcinoma cells. The human OCT4 gene can generate at least three variants (OCT4A, OCT4B, and OCTB1) via alternative splicing and ...
Ensieh M Poursani, Majid Mehravar, Bahram Mohammad Soltani, Seyed Javad Mowla   +3 more
doaj   +1 more source

Current perspectives of the signaling pathways directing neural crest induction. [PDF]

, 2012
The neural crest is a migratory population of embryonic cells with a tremendous potential to differentiate and contribute to nearly every organ system in the adult body.
García-Castro, Martín I, Stuhlmiller, Timothy J   +1 more
core   +2 more sources

Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. [PDF]

, 2015
BackgroundAdenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in ...
Bellusci, Saverio, Chen, Hui, Chiu, Joanne, El Agha, Elie, Luo, Yongfeng, Menke, Douglas B, Qian, Bang-Ping, Shi, Wei, Turcatel, Gianluca, Warburton, David   +9 more
core   +1 more source

Gene regulatory network interactions in sea urchin endomesoderm induction. [PDF]

PLoS Biology, 2009
A major goal of contemporary studies of embryonic development is to understand large sets of regulatory changes that accompany the phenomenon of embryonic induction. The highly resolved sea urchin pregastrular endomesoderm-gene regulatory network (EM-GRN)
Aditya J Sethi, Robert C Angerer, Lynne M Angerer   +2 more
doaj   +1 more source

Neuronal induction and regional identity by co-culture of adherent human embryonic stem cells with chicken notochords and somites [PDF]

The role of somites and notochords in neuroectoderm differentiation from the embryonic ectoderm and its subsequent patterning into regional compartments along rostro-caudal and dorso-ventral axes, especially in humans, remains elusive.
بهاروند, حسين, تنهايي, سميه, رضوي, شهناز, سقا, محسن, صالحی, حسین, نصر اصفهاني, محمد حسين, نعمت الهی, مرضیه, کربلایی, خدیجه   +7 more
core   +1 more source

Establishment of an Embryonic Tip Regeneration System of Soybean

Brazilian Archives of Biology and Technology
In order to establish an optimal soybean embryonic tip regeneration system that can serve as soybean genetic transformation receptor, and be used for the study of genetic function verification, the influences of single factor on the adventitious bud of ...
LIU Si-yan, LI Guang-long, QU Jing, GUAN Shu-yan, YAO Dan, WANG Pi-wu, LIU Si-chen, JIA Yang, GUAN Peng-fei, WANG Long-qing   +9 more
doaj   +1 more source

Generation of human pluripotent stem cell lines with suppressed expression of the Notch ligand DLL4 using short hairpin RNAs

Stem Cell Research, 2016
Studies with different animal models have shown that the Notch ligand DLL4 has a key role in the development of the embryonic vasculature. Here we describe the generation and characterization of a human embryonic stem cell line and an induced pluripotent
Federico González-Pozas, Rosa Montes, Lourdes López-Onieva, Tamara Romero, Joan Domingo-Reinés, Pedro J. Real, Verónica Ramos-Mejía, Verónica Ayllón   +7 more
doaj   +1 more source

Experiments on Embryonic Induction [PDF]

Journal of Experimental Biology, 1934
ABSTRACT It is shown that the ectoderm of the area opaca of chick embryos of the primitive streak stage can react to primitive streak grafts by the formation of an induced neural plate. The conclusion is drawn that the competence to form neural plate is not conferred on ectoderm by the gut endoderm, which determines the formation of the ...
openaire   +2 more sources