Results 91 to 100 of about 655,926 (306)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Exigências de lisina e energia metabolizável para marrãs de reprodução Lysine and metabolyzable energy requirements for breeding gilts

Revista Brasileira de Zootecnia, 2005
Objetivando-se determinar os níveis de lisina (Lis) e energia metabolizável (EM) para marrãs de reprodução, foram utilizadas 108 marrãs Seghers® (Large-White x Landrace/Large-White), submetidas a um delineamento inteiramente casualizado, em esquema ...
José Maurício Gonçalves dos Santos, Ivan Moreira, Elias Nunes Martins   +2 more
doaj   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

An unusual finding of Sepietta oweniana (Cephalopoda: Sepiolidae) egg clutch

Scientia Marina, 2010
An unusual finding of Sepietta oweniana egg clutch at 544 m depth is described within an updating study of the reproductive aspects of the species in Sardinian waters.
Danila Cuccu, Marco Mereu, Rita Cannas, Sandro Marcias, Angelo Cau, Patrizia Jereb   +5 more
doaj   +1 more source

The Formation of Brown Dwarfs as Ejected Stellar Embryos [PDF]

, 2001
We conjecture that brown dwarfs are substellar objects because they have been ejected from small newborn multiple systems which have decayed in dynamical interactions.
Armitage P. J., Armitage P. J., Bo Reipurth, Boffin H. M. J., Bonnell I. A., Burkert A., Cameron A., Cathie Clarke, Clarke C. J., Clarke C. J., Comeron F., de la Fuente Marcos R., Goldman B., Halbwachs J. L., Hall S. M., Herbig G. H., Kohler R., Kroupa P., Larson R. B., Larson R. B., McDonald J. M., McDonald J. M., Pringle J. E., Reipurth B., Smith K. W., Sterzik M. F., Sterzik M. F., van Albada T. S., Watkins S. J., Watkins S. J.   +29 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

The Role of Transplacental Infection in Leptospira spp. Epidemiology in Cattle in Caatinga Biome, Brazil

Microorganisms
Leptospirosis is an infectious disease that affects domestic animals, wild animals, and humans. It represents a public health problem and has an important economic impact on livestock.
Nathanael Natércio da Costa Barnabé, Rafael Rodrigues Soares, Deivyson Kelvis Silva Barros, João Pessoa Araújo Júnior, Camila Dantas Malossi, Maria Luana Cristiny Rodrigues Silva, Arthur Willian de Lima Brasil, Diego Figueiredo da Costa, Severino Silvano dos Santos Higino, Carolina de Sousa Américo Batista Santos, Sérgio Santos de Azevedo, Clebert José Alves   +11 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Karyotype characterization, constitutive heterochromatin and nucleolus organizer regions of Paranaita opima (Coleoptera, Chrysomelidae, Alticinae)

Genetics and Molecular Biology, 2006
Species of the subtribe Oedionychina not only have a highly uniform diploid number of 2n = 22 (20+X+y) but have the karyotypic peculiarity of possessing extremely large sex chromosomes.
Mara Cristina de Almeida, Carlos Campaner, Doralice Maria Cella   +2 more
doaj   +1 more source

Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome [PDF]

, 1995
MRF4 (herculin/Myf-6) is one of the four member MyoD family of transcription factors identified by their ability to enforce skeletal muscle differentiation upon a wide variety of nonmuscle cell types.
Miner, Jeffrey H., Patapoutian, Ardem, Stark, Kevin, Wang, Shuling, Wold, Barbara, Yoon, Jeong Kyo   +5 more
core