Results 51 to 60 of about 808,443 (353)
Methanol and isopropanol embryo dosage response curves for wild-type and ethanol-sensitive zebrafish [PDF]
It is well established that ethanol has an array of negative effects on developing embryos, from craniofacial abnormalities to cognitive deficits and behavioral disorders.
Anderson, Ashley
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Objetivando-se determinar os níveis de lisina (Lis) e energia metabolizável (EM) para marrãs de reprodução, foram utilizadas 108 marrãs Seghers® (Large-White x Landrace/Large-White), submetidas a um delineamento inteiramente casualizado, em esquema ...
José Maurício Gonçalves dos Santos +2 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Peroxisome proliferator-activated receptors (PPARs), a nuclear receptors for prostacyclin (PGI2) have been recognized as being essential for early embryo development.
Katarzyna Suwik +6 more
doaj +1 more source
Subtle but significant effects of CO
Our understanding of the effects of ocean acidification on whole organism function is growing, but most current information is for adult stages of development.
Bersey, J +4 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
This study was designed to explore the effects of histone deacetylase inhibitor romidepsin (FK228) treatment on the morphology, proliferation and karyotype of porcine foetal fibroblast cells and early developmental competence of somatic cell nuclear ...
Zhangfan Wang +8 more
doaj +1 more source
Vital dye labelling demonstrates a sacral neural crest contribution to the enteric nervous system of chick and mouse embryos [PDF]
We have used the vital dye, DiI, to analyze the contribution of sacral neural crest cells to the enteric nervous system in chick and mouse embryos. In order to label premigratory sacral neural crest cells selectively, DiI was injected into the lumen of ...
Bronner-Fraser, Marianne +3 more
core
Embryo culture in presence of oviductal fluid induces DNA methylation changes in bovine blastocysts [PDF]
During the transit through the oviduct, the early embryo initiates an extensive DNA methylation reprogramming of its genome. Given that these epigenetic modifications are susceptible to environmental factors, components present in the oviductal milieu ...
Barrera, Antonio Daniel +7 more
core +1 more source

