Results 61 to 70 of about 655,926 (306)

The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo [PDF]

, 2005
Maternal and zygotic activities of the homeodomain protein PAL-1 specify the identity and maintain the development of the multipotent C blastomere lineage in the C. elegans embryo. To identify PAL-1 regulatory target genes, we used microarrays to compare
Baugh, L. Ryan, Brown, Eugene L., Claggett, Julia M., Hill, Andrew A., Hill-Harfe, Kate, Hunter, Craig P., Slonim, Donna K., Wen, Joanne C.   +7 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Effects of Short-Term Differences in Concentrate Feeding on the Recovery of In Vivo Embryos in Hanwoo Donor Cows through Superovulation Treatment

Animals
Superovulation is a technique used to increase the number of oocytes released for fertilization. This study investigated the effects of short-term differences in concentrate feed intake on in vivo embryo production through superovulation in indigenous ...
Seungmin Ha, Namtae Kim, Mi-Ryung Park, Seyoung Lee, Sang-Rae Cho, Huimang Song, Daehyeok Jin, Ui-Hyung Kim, Yeoung-Gyu Ko   +8 more
doaj   +1 more source

Embryonic POU5F1 is Required for Expanded Bovine Blastocyst Formation. [PDF]

, 2018
POU5F1 is a transcription factor and master regulator of cell pluripotency with indispensable roles in early embryo development and cell lineage specification.
Daigneault, Bradford W, Rajput, Sandeep, Ross, Pablo J, Smith, George W   +3 more
core   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Vital dye labelling demonstrates a sacral neural crest contribution to the enteric nervous system of chick and mouse embryos [PDF]

, 1991
We have used the vital dye, DiI, to analyze the contribution of sacral neural crest cells to the enteric nervous system in chick and mouse embryos. In order to label premigratory sacral neural crest cells selectively, DiI was injected into the lumen of ...
Bronner-Fraser, Marianne, Burgan, Scott, Fraser, Scott E., Serbedzija, George N.   +3 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

SOMITE NUMBER EVOLUTION DURING EARLY EMBRYOGENESIS IN CHICKEN EMBRYOS FROM TRANSYLVANIAN NAKED NECK AND PLYMOUTH ROCK BREEDS

Scientific Papers Animal Science and Biotechnologies, 2023
In Romania, the Transylvanian Naked Neck hen breed is considered to be an “endangered” population, reason for which we consider that a special attention should have been given until now. Plymouth Rock breed was imported for the first time to Romania from
D. DRONCA, N. PĂCALĂ, I. BENCSIK, LAVINIA ȘTEF, RODICA CĂPRIŢĂ, T. OROIAN, MIHAELA IVANCIA, LILIANA BOCA   +7 more
doaj  

“So, what is an embryo?” A comparative study of the views of those asked to donate embryos for hESC research in the UK and Switzerland

New Genetics and Society, 2008
The moral status of the human embryo has gained much attention in debates over the acceptability, or otherwise, of human embryonic stem cell research.
Erica Haimes, Rouven Porz, Jackie Scully, Christoph Rehmann-Sutter   +3 more
doaj   +1 more source