Results 51 to 60 of about 793,756 (249)
BMC Public HealthBackground Non-governmental organizations support state-based responses to health emergencies, including the COVID-19 pandemic. Their capacity to respond effectively to such emergencies depends on worker and volunteer willingness to engage in high-risk ...
Leonardo W. Heyerdahl +4 more
doaj +1 more source
Cogent Food & AgricultureWe report the first outbreak of a pathogenic avian influenza virus that occurred on 13 April 2022 in the locality of Meyang, in Gabon, causing the death of 17,498 laying hens.
Gael Darren Maganga +10 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Complete coding sequence of Zika virus from Martinique outbreak in 2015
New Microbes and New Infections, 2016 Zika virus is an Aedes-borne Flavivirus causing fever, arthralgia, myalgia rash, associated with Guillain–Barré syndrome and suspected to induce microcephaly in the fetus.
G. Piorkowski +6 more
doaj +1 more source
Severe COVID-19: what have we learned with the immunopathogenesis?
Advances in Rheumatology, 2020 The COVID-19 outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global major concern. In this review, we addressed a theoretical model on immunopathogenesis associated with severe COVID-19, based on the current ...
Bruno Bordallo +4 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Emerging Sight, Emerging Blindness
, 2012 This essay covers two main topics: the role of the “double vi-sion” of the sight/nonsight of blinking in selected fiction of Neil Gaiman and China Miéville, and an examination of the role of blindness and sight surrounding “Molyneux’s question.” In Gaiman’s work “double vision” functions as a synchronic representation of diachronic events.
openaire +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
No evidence of mpox virus circulation in putative animal reservoirs in Gabon wildlife
International Journal of Infectious DiseasesObjectives: Mpox is a neglected viral endemic tropical disease in Central and Western African countries transmitted to humans by an animal. However, the natural reservoir of the virus remains elusive.
Nadine N'dilimabaka +11 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source