Results 41 to 50 of about 3,349,217 (305)
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Abstract ‘Emergence’ looks at the relations between building blocks, generated systems, and the phenomenon of emergence. To understand emergent phenomena, it is necessary to describe the emergence of a system’s behaviour from the non-additive interactions of its building blocks. Emergence occurs when the generators for a generated system
openaire +1 more source
Cities: Continuity, transformation and emergence [PDF]
Book synopsis: This book applies ideas and methods from the complexity perspective to key concerns in the social sciences, exploring co-evolutionary processes that have not yet been addressed in the technical or popular literature on complexity.
Barros, J, Batty, M, Júnior, SA
core
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Objectives To evaluate the knowledge, attitudes and practices towards diagnosing and managing paediatric sepsis among paediatric physicians and nurses.Design A cross-sectional, questionnaire-based study.Setting 21 hospitals in Hubei Province between ...
Jie Li +4 more
doaj +1 more source
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman +8 more
wiley +1 more source
There are many requirements, issues and complexities that engineering design problems must take into account, and these engineering items are often treated as constraints in optimization problems.
So FUKUHARA +2 more
doaj +1 more source
Impact of the combined presence of left ventricular systolic and renal dysfunction on the 5-year outcome after ST-elevation myocardial infarction [PDF]
Background/Aim. The coincidence of left ventricular systolic dysfunction (LVSD) and renal dysfunction (RD) is a strong independent predictor of adverse events in the short-term and mid-term follow-ups of patients with ST-elevation myocardial ...
Savić Lidija +6 more
doaj +1 more source
Emerging Options for Emergency Contraception [PDF]
Emergency post-coital contraception (EC) is an effective method of preventing pregnancy when used appropriately. EC has been available since the 1970s, and its availability and use have become widespread. Options for EC are broad and include the copper intrauterine device (IUD) and emergency contraceptive pills such as levonorgestrel, ulipristal ...
Atsuko Koyama +2 more
openaire +4 more sources
Ongoing Emergence: A Core Concept in Epigenetic Robotics [PDF]
We propose ongoing emergence as a core concept in epigenetic robotics. Ongoing emergence refers to the continuous development and integration of new skills and is exhibited when six criteria are satisfied: (1) continuous skill acquisition, (2 ...
Helder, Nathan +2 more
core +1 more source

