Results 111 to 120 of about 157,712 (208)

Assessing technical aspects and vulnerabilities from Tswaing informal settlement in Hammanskraal, South Africa

Jàmbá
The increasing frequency of hazards such as floods, droughts, socio-political unrest, emerging diseases and rising temperatures has affected South Africa.
Davies V. Nkosi, Patience Mbola, Evelyn R. Maleka, Dikeledi M. Mapheto, Engetelo P. Ngwenya, Thabang S. Mokwena, Silas Mohlala, Nchang J. Langa, Lethabo S. Kgopa, Octavia M. Komane   +9 more
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Excreta Disposal in Emergencies: A field manual [PDF]

, 2004
The purpose of the manual is to provide practical guidance on how to select, design, construct and maintain appropriate excreta disposal systems in emergency situations.
Piano, Edoardo, Bastable, Andy, Hoque, Enamul, Morris, Leslie, Smith, Mel, Harvey, Peter, Ferron, Suzanne, Forster, Tim   +7 more
core  

Intraoperative emergencies

, 2016
This chapter describes intraoperative emergencies, including haemorrhage, perforated uterus, and damage to the urinary tract, blood vessels, or bowel, and details the recommended treatment options for each of these emergencies.
Vikram S. Talaulikar, S. Arulkumaran, Stergios K. Doumouchtsis   +2 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Reasons for encounters, diagnoses, and admission rate among emergency referrals at an urban primary care clinic in Japan: A retrospective cohort study

Journal of General and Family Medicine
Background Comprehensive understanding of emergency referrals (EmR), encompassing reasons for encounters (RFEs) and diagnoses, is crucial for primary care physicians (PCPs).
Yoshinao Satoi, Masato Matsushima, Hiroyoshi Iwata   +2 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Experts' Views on Factors Influencing Resource Allocation for Infectious Disease Emergencies Based on Humanitarian Principles: A Qualitative Study

AJPM Focus
Introduction: Infectious diseases can result in global emergencies and a shortage of resources, leading to ethical and humanitarian challenges. This study aimed to identify the factors that affect the allocation of health resources based on humanitarian ...
Mohammad Reza Fallah Ghanbari, PhDc, Katayoun Jahangiri, PhD, Mehdi Safari, PhD, Zohreh Ghomian, PhD, Mohammad Ali Nekooie, PhD   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Train operation in emergencies

, 2017
This book presents the latest findings on train operation theories and methods in the context of emergencies. It examines and assesses a range of aspects—including the definition of a railway emergency, transport organization modes in emergencies ...
Jia, Limin, Limin Jia, Yong Qin, Meng, Xuelei, Qin, Yong, Xuelei Meng   +5 more
core   +1 more source