Results 51 to 60 of about 1,738,349 (311)

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

‘A tale of two paradoxes in response to COVID-19’: Public health system and socio-economic implications of the pandemic in South Africa and Zimbabwe.

Cogent Social Sciences, 2021
Africa’s response to the outbreak of infectious diseases has come under scrutiny over the years and the outbreak of COVID-19 has exacerbated the situation.
Bellita Banda Chitsamatanga, Wayne Malinga   +1 more
doaj   +1 more source

Penalties for Emergency Medical Treatment and Labor Act Violations Involving Obstetrical Emergencies [PDF]

, 2020
Introduction: The Emergency Medical Treatment and Labor Act (EMTALA) was intended to prevent inadequate, delayed, or denied treatment of emergent conditions by emergency departments (ED). While controversies exist regarding the scope of the law, there is
Arora, Sanjay, Burner, Elizabeth, Menchine, Michael, Terp, Sophie, Wang, Brandon   +4 more
core  

Design of vaccine efficacy trials during public health emergencies

Science Translational Medicine, 2019
This Perspective describes key considerations for the design and analysis of candidate vaccine trials during public health emergencies. Public health emergencies, such as an Ebola disease outbreak, provide a complex and challenging environment for the ...
N. Dean, P. Gsell, R. Brookmeyer, V. Gruttola, Christl A. Donnelly, Christl A. Donnelly, M. Halloran, M. Halloran, Momodou Jasseh, M. Nason, Ximena Riveros, C. Watson, A. Henao-Restrepo, I. Longini   +13 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

СONSTRUCTION AND THE ALGORITHM OPERATION OF THE LASER COMBINED FIRE DETECTOR

Приборы и методы измерений, 2017
The point optical smoke detector is currently the most effective means of fire detection at the early stage of its occurrence. The urgent task for this type of detector is to increase its sensitivity to «black» smoke and ensure resilience to the effects ...
A. I. Kitsak, A. P. Lushchyk, D. L. Esipovich, V. N. Konon, I. V. Kavalchyk, O. A. Protasevich, I. B. Tretyak   +6 more
doaj   +1 more source

In-Flight Medical Emergencies: A Review

Journal of the American Medical Association (JAMA), 2018
Importance In-flight medical emergencies (IMEs) are common and occur in a complex environment with limited medical resources. Health care personnel are often asked to assist affected passengers and the flight team, and many have limited experience in ...
C. Martin-Gill, T. Doyle, D. Yealy
semanticscholar   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Impediments to and impact of checklists on performance of emergency interventions in primary care: an in situ simulation-based randomized controlled trial

Scandinavian Journal of Primary Health Care, 2021
Objective Medical crises occur rather seldom in the primary care setting, but when they do, initial management impacts on morbidity and mortality. Factors that impede the performance of emergency interventions in primary care have not been studied ...
Eric Dryver, Jeanette Knutsson, Ulf Ekelund, Anders Bergenfelz   +3 more
doaj   +1 more source

Enfoque del tromboembolismo pulmonar agudo desde el momento inicial en el servicio de urgencias

Medicina U.P.B., 2021
El tromboembolismo pulmonar es la manifestación más grave de la enfermedad tromboembólica venosa y la tercera causa de mortalidad cardiovascular. Su sintomatología puede ir desde un cuadro asintomático o con síntomas leves, hasta el paro cardiaco. Dentro
Laura Restrepo Álvarez, Andrés Ramírez Vélez, Marcela Pérez Muñoz, Juan Pablo Zuluaga García, Jairo Giovanni Moncayo Viveros   +4 more
doaj   +1 more source