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Emerging Options for Emergency Contraception [PDF]

Clinical Medicine Insights: Reproductive Health, 2013
Emergency post-coital contraception (EC) is an effective method of preventing pregnancy when used appropriately. EC has been available since the 1970s, and its availability and use have become widespread. Options for EC are broad and include the copper intrauterine device (IUD) and emergency contraceptive pills such as levonorgestrel, ulipristal ...
Atsuko Koyama, Laura Hagopian, Judith Linden   +2 more
openaire   +4 more sources

What School Principals Need to Know About Curriculum and Instruction [PDF]

, 2001
Looks at what school leaders need to know about instructional practices, organizing a school for greater student learning, supporting teacher development, and balancing school improvement with non-instructional issues and ...
Gene Bottoms
core  

Penalties for Emergency Medical Treatment and Labor Act Violations Involving Obstetrical Emergencies [PDF]

, 2020
Introduction: The Emergency Medical Treatment and Labor Act (EMTALA) was intended to prevent inadequate, delayed, or denied treatment of emergent conditions by emergency departments (ED). While controversies exist regarding the scope of the law, there is
Arora, Sanjay, Burner, Elizabeth, Menchine, Michael, Terp, Sophie, Wang, Brandon   +4 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Crowdsourced Rumour Identification During Emergencies [PDF]

, 2015
When a significant event occurs, many social media users leverage platforms such as Twitter to track that event. Moreover, emergency response agencies are increasingly looking to social media as a source of real-time information about such events ...
Macdonald, Craig, Mccreadie, Richard, Ounis, Iadh   +2 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

СONSTRUCTION AND THE ALGORITHM OPERATION OF THE LASER COMBINED FIRE DETECTOR

Приборы и методы измерений, 2017
The point optical smoke detector is currently the most effective means of fire detection at the early stage of its occurrence. The urgent task for this type of detector is to increase its sensitivity to «black» smoke and ensure resilience to the effects ...
A. I. Kitsak, A. P. Lushchyk, D. L. Esipovich, V. N. Konon, I. V. Kavalchyk, O. A. Protasevich, I. B. Tretyak   +6 more
doaj   +1 more source

Factors influencing hospital emergency evacuation during fire: A systematic literature review

International Journal of Preventive Medicine, 2021
Background: Although the hospital is known as a safe place for treating patients, due to various reasons, it is prone to several internal hazards, including fire.
Ali Sahebi, Katayoun Jahangiri, Ahmad Alibabaei, Davoud Khorasani-Zavareh   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

EMERGENT RELATIVITY [PDF]

International Journal of Modern Physics A, 2003
A possible resolution of the incompatibility of quantum mechanics and general relativity is that the relativity principle is emergent. I show that the central paradox of black holes also occurs at a liquid-vapor critical surface of a bose condensate but is resolved there by the phenomenon of quantum criticality.
openaire   +3 more sources