Results 71 to 80 of about 953,645 (368)

Building Leaderful Organizations: Succession Planning for Nonprofits [PDF]

, 2008
Shares three approaches to planning for new leadership -- ongoing leadership development, planning for emergencies, and planning for a departure announced well in advance.
Tim Wolfred
core  

Oncologic Emergencies: Immune-Based Cancer Therapies and Complications [PDF]

, 2020
Cancer therapies have undergone several recent advancements. Current cancer treatments include immune-based therapies comprised of checkpoint inhibitors, and adoptive immunotherapy; each treatment has the potential for complications that differ from ...
Brém, Elizabeth, Koyfman, Alex, Long, Brit Jeffrey   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Rescue Model for the Bystanders' Intervention in Emergencies

, 2005
To investigate an effect of social interaction on the bystanders' intervention in emergency situations we introduce a rescue model which includes the effects of the victim's acquaintance with bystanders and those among bystanders.
, Bernardes A. T., De May J., H.-H Jo, H.-T Moon, Hołyst J. A., Kohring G. A., Latané B., Mantegna R. N., Piliavin J. A., Rasenberger J., Stauffer D., Vallacher R. R., W.-S Jung   +13 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Using Technology to Enhance Rural Resilience in Pre-hospital Emergencies [PDF]

, 2015
The research presented in this paper is supported by RCUK dot.rural Digital Economy Research Hub, University of Aberdeen [grant number EP/G066051/1].Peer reviewedPublisher ...
Kindness, Peter, Mellish, Chris, Mort, Alasdair, Reiter, Ehud, Schneider, Anne Helen, Wilson, Philip   +5 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Post-disaster housing and management in Malaysia: a literature review [PDF]

, 2013
Purpose – Malaysia is still in the process of reorganising and restructuring disaster management policy, learning from the national and international experiences.
O'Keefe, Phil, Roosli, Ruhizal
core   +2 more sources

Emerging Sight, Emerging Blindness

, 2012
This essay covers two main topics: the role of the “double vi-sion” of the sight/nonsight of blinking in selected fiction of Neil Gaiman and China Miéville, and an examination of the role of blindness and sight surrounding “Molyneux’s question.” In Gaiman’s work “double vision” functions as a synchronic representation of diachronic events.
openaire   +1 more source