Results 41 to 50 of about 931,347 (253)
Abstract ‘Emergence’ looks at the relations between building blocks, generated systems, and the phenomenon of emergence. To understand emergent phenomena, it is necessary to describe the emergence of a system’s behaviour from the non-additive interactions of its building blocks. Emergence occurs when the generators for a generated system
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‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
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Agostino Di Scipio refers in his works to theoretical implications of system theory and transfers its models into his compositions, installations, and recently into his sounding objects. Some of these references are mentioned in this paper and the transfer is looked at. In interactive real-time compositions like Di Scipio’s Audible ecosystemics series (
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An Emergency within an Emergency within an Emergency
Verfassungsblog: On Matters ...
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How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Local and tribal emergency managers
Began with May 1, 2018Mode of access: Internet from the Oregon Government Publications CollectionText in EnglishIssued by: Oregon Emergency Management, -May 2022; by: Oregon Department of Emergency Management, July 2022-This archived document is ...
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Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
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Biweekly, May 25, 2007-Sept. 29, 2008.; Weekly, -May 11, 2007.; Electronic coverage as of Sept. 5, 2014: Vol. 3, no. 1 (Jan. 6, 2006)-v. 5, no. 17 (Sept. 29, 2008); "A publication of the Ohio Emergency Management Agency, a division of the Ohio Department
Ohio Emergency Management Agency.
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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