Results 61 to 70 of about 1,302,356 (300)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Predictability of the emergency department triage system during the COVID-19 pandemic [PDF]

Clinical and Experimental Emergency Medicine
Objective Emergency department (ED) triage systems are used to classify the severity and urgency of emergency patients, and Korean medical institutions use the Korean Triage and Acuity Scale (KTAS). During the COVID-19 pandemic, appropriate treatment for
Se Young Oh, Ji Hwan Lee, Min Joung Kim, Dong Ryul Ko, Hyun Soo Chung, Incheol Park, Jinwoo Myung   +6 more
doaj   +1 more source

Addressing overcrowding in an emergency department: an approach for identifying and treating influential factors and a real-life application

Israel Journal of Health Policy Research, 2020
Background Overcrowding in hospital emergency departments that arises from long length-of-stay is an unfortunate common occurrence. While some factors affecting length-of-stay are well known, there may be additional factors that have not yet been ...
Guy Wachtel, Amir Elalouf
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A genetic algorithm for dynamic scheduling in emergency departments with priorities [PDF]

, 2011
A hospital is a very complex environment and its management is a hard task. The point we explore in this thesis is the management of the patient flow for the Emergency Department. The main contribution of the thesis is twofold: on the one hand, we design
Bergamin, Filippo
core  

Emergency nurse practitioners and doctors consulting with patients in an emergency department : a comparison of communication skills and satisfaction [PDF]

, 2009
Background: Emergency nurse practitioners (ENPs) play an increasingly important role in UK emergency departments (EDs), but there is limited evidence about how this affects patient care and outcome.
Crouch, R., Sandhu, Harbinder, Glucksman, E., Dale, Jeremy, Stallard, Nigel   +4 more
core   +1 more source

Process flows of an emergency department. How process modelling and simulation can help improve the efficiency and quality of patient care [PDF]

SHS Web of Conferences
Emergency departments are the first point of contact for life-saving care worldwide. Despite this importance in patient care, emergency departments face a number of shortcomings. For example, emergency departments have been struggling for many years with
Angler Yannik, Loßin Astrid, Goetz Olav
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Primary care in accident and emergency departments : the cost effectiveness and applicability of a new model of care. [PDF]

The thesis describes the development, research and evaluation of the applicability of a new model of care that involves GPs being employed on a sessional basis in A&E departments to treat patients attending with primary care needs.
Dale, Jeremy
core   +1 more source

Management Patterns of Croup in Korean Emergency Departments: A Nationwide Cohort Study

Children
Background: Despite the established importance of prescribing steroids to children with croup, many physicians in Korean emergency departments (EDs) do not adhere to this recommendation.
Jin Hee Kim, Jae Yun Jung, Soyun Hwang, Joong Wan Park, Eui Jun Lee, Ha Ni Lee, Do Kyun Kim, Young Ho Kwak   +7 more
doaj   +1 more source