Results 41 to 50 of about 61,831 (226)

Frequent callers vs. frequent users – a scoping review of frequent contacts to the emergency medical services

International Journal of Emergency Medicine
Background A significant limitation in the literature on frequent callers and frequent users of prehospital Emergency Medical Services (EMS) is the lack of consistent and thus, comparable definitions, as well as inconsistent use of terminology.
Astrid Karina Valås Harring, Maria Kjærgaard, Tine Bennedsen Gehrt   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A comparison of two emergency medical dispatch protocols with respect to accuracy

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2017
Background Emergency medical dispatching should be as accurate as possible in order to ensure patient safety and optimize the use of ambulance resources.
Klara Torlén, Lisa Kurland, Maaret Castrén, Knut Olanders, Katarina Bohm   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Stroke detection in medical emergency calls: a retrospective analysis and exploratory evaluation of an AI decision support model

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Timely identification of acute stroke during medical emergency calls is critical for optimizing patient outcomes. We aimed to (i) characterize the prehospital trajectories of patients with stroke and (ii) explore the ability of an artificial ...
Emil Iversen, Hege Ihle-Hansen, Kari Krizak Halle, Alexander Selvikvåg Lundervold, Lars Myrmel, Anders Strand Vestbø, Annette Fromm, Cosimo Damiano Persia, Christian Autenried, Guttorm Brattebø   +9 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Hiper utilizadores e urgência.

Acta Médica Portuguesa, 2009
The emergency service is the source of medical assistance for users in need of other medical care. The hyperusers make substantial part of the emergency services and their impact on the health system is unknown.To know the pattern of the emergency unit ...
Agripino Oliveira
doaj   +1 more source

Health Effects of Wildfires Reported in Emergency Medical Communication Centres: An Ecological Study in Gironde District, France, during the Summer of 2022

, 2023
Wildfires are a rising environmental threat which health impact remains poorly documented, in particular beyond the fire period. This ecological study investigates changes in health conditions before, during, and after two consecutive wildfires that occurred in France´s Gironde district in the summer 2022.
Eklof, Sofia, Lagarde, Emmanuel, Tellier, Eric, Russon, Dylan, Pradeau, Catherine, Laflamme, Lucie, Gil-Jardine, Cedric   +6 more
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source