Results 31 to 40 of about 61,831 (226)

Additional file 4 of Emergency physician’s dispatch by a paramedic-staffed emergency medical communication centre: sensitivity, specificity and search for a reference standard

, 2021
Additional file 4. “Diagnostic test” for each symptom using NACA ≥5 as reference standard. This table shows the “diagnostic test” applied for each of the 53 symptoms, thus detailing the sensitivity, specificity, positive & negative predictive values, over-triage & under-triage with their respective 95% confidence intervals for each symptom when
Chappuis, Victor Nathan, Deham, Hélène, Cottet, Philippe, Gartner, Birgit Andrea, Sarasin, François Pierre, Niquille, Marc, Suppan, Laurent, Larribau, Robert   +7 more
openaire   +2 more sources

Additional file 3 of Emergency physician’s dispatch by a paramedic-staffed emergency medical communication centre: sensitivity, specificity and search for a reference standard

, 2021
Additional file 3. “Diagnostic test” for each symptom using NACA ≥4 as reference standard. This table shows the “diagnostic test” applied for each of the 53 symptoms, thus detailing the sensitivity, specificity, positive & negative predictive values, over-triage & under-triage with their respective 95% confidence intervals for each symptom when
Chappuis, Victor Nathan, Deham, Hélène, Cottet, Philippe, Gartner, Birgit Andrea, Sarasin, François Pierre, Niquille, Marc, Suppan, Laurent, Larribau, Robert   +7 more
openaire   +2 more sources

Correlation between the accuracy of the emergency response centre’s urgency assessment and emergency medical services non-conveyance: a retrospective register-based study in Finland

BMC Emergency Medicine
Background In modern emergency medical services (EMS), ambulances increasingly focus on examining and treating the patient at the scene. This has led to increased levels of non-conveyance. In Finland, for instance, approximately 40% of EMS dispatches end
Tomi Salminen, Kaius Kaartinen, Mira Palonen, Piritta Setälä, Eija Paavilainen, Sanna Hoppu   +5 more
doaj   +1 more source

Evaluating call prioritisation discrepancies and Emergency Medical Services resource allocation in the North West province of South Africa

African Journal of Emergency Medicine
The overwhelming flow of non-emergent cases burdens Emergency Medical Services (EMS), reducing their capacity to respond to life-threatening emergencies and compromising care for patients with emergent clinical needs.
Bongumusa N. Mbatha, Simpiwe Sobuwa, Ntuthuko G. Chule   +2 more
doaj   +1 more source

Additional file 1 of Emergency physician’s dispatch by a paramedic-staffed emergency medical communication centre: sensitivity, specificity and search for a reference standard

, 2021
Additional file 1. Prevalence of main symptoms, NACA ≥4 & NACA ≥5, 1st & 2nd- line dispatch. This table shows the prevalence of the main symptoms identified during the call, the prevalence respectively of NACA ≥4 and NACA ≥5 found on site for each symptom, and the prevalence of 1st & 2nd line dispatch of the emergency physician for each ...
Chappuis, Victor Nathan, Deham, Hélène, Cottet, Philippe, Gartner, Birgit Andrea, Sarasin, François Pierre, Niquille, Marc, Suppan, Laurent, Larribau, Robert   +7 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The importance of lay descriptors of respiratory symptoms: a retrospective analysis of under-triaged emergency calls

Emergency Care Journal
Accurate triage of respiratory emergencies during emergency calls is critical but may be compromised when dispatchers misinterpret lay language. Nonspecific descriptors may be perceived as the presence of breathing despite indicating severe conditions ...
Guglielmo Imbriaco, Juliette Masina, Giorgia Ghedini, Gianluca Federiconi, Jihan Samira Kayal, Diana Demaria, Jacopo Davide Giamello   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source