Results 101 to 110 of about 6,009,367 (279)

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Long‐Chain Molecule Reconstruction of Novel Solvation Structure to Stabilize Zinc Metal Anode

Advanced Science, EarlyView.
Triethylene glycol diacetate (TGD), with unique long‐chain characteristics and rich oxygen‐containing functional groups, was used as an electrolyte additive to reconstruct the solvation structure. TGD can reduce the erosion of H2O molecules on the Zn anode, effectively homogenize the electric field distribution. Therefore, the Zn//Zn symmetric cell can
Changdong Chen, Lingwei Xue, Gaojie Li, Xueli Chen, Yongjun Han, Liwei Mi, Yuqing Chen   +6 more
wiley   +1 more source

Impact of drone-specific dispatch instructions on the safety and efficacy of drone-delivered emergency medical treatments: A randomized simulation pilot study

Resuscitation Plus
Introduction: Medical drones have potential for improving the response times to out-of-hospital emergencies. However, widespread adoption is hindered by unanswered questions surrounding medical dispatch and bystander safety.
Emma E. Davidson, Jason A Correll, Adam Gottula, Laura R. Hopson, Thomas B Leith, Noor K. Majhail, Emily J. Mathias, James M Pribble, Nathan B. Roberts, Isabella G. Scott, James A. Cranford, Nathaniel Hunt, Christine M. Brent   +12 more
doaj   +1 more source

Optimizing an Emergency Medical Dispatch System to Improve Prehospital Diagnosis and Treatment of Acute Coronary Syndrome: Nationwide Retrospective Study in China. [PDF]

J Med Internet Res, 2022
Dong X, Ding F, Zhou S, Ma J, Li N, Maimaitiming M, Xu Y, Guo Z, Jia S, Li C, Luo S, Bian H, Luobu G, Yuan Z, Shi H, Zheng ZJ, Jin Y, Huo Y.   +17 more
europepmc   +1 more source

Further Evidences for the Sulfur Spillover on Carbon: Thermodynamic Aspects and Effects on Li‐S Solid‐State Batteries

Advanced Science, EarlyView.
ABSTRACT This study investigates sulfur spillover, the spontaneous and rapid spread of sulfur over carbon surfaces at ambient temperature. The process is studied by small‐angle X‐ray scattering (SAXS), X‐ray radiography, and microcalorimetry from which a number of physicochemical properties are derived.
Francesco Piccolo, Anka Berger, Sebastian Risse, Román Healy Corominas, Wilhelm Erth, Florian Fuchs, Jesus Andrade, Jörg Schuster, Marc Armbrüster, Philipp Adelhelm   +9 more
wiley   +1 more source

EMCC dispatch priority for trauma patients in Norway: a retrospective cohort study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Dispatch priority assessments in emergency medical communication centres (EMCC) play a crucial role in determining how quickly emergency medical services reach the scene after an injury.
Inger Marie Waal Nilsbakken, Torben Wisborg, Stephen Sollid, Elisabeth Jeppesen   +3 more
doaj   +1 more source

Machine Learning-Based Text Analysis to Predict Severely Injured Patients in Emergency Medical Dispatch: Model Development and Validation. [PDF]

J Med Internet Res, 2022
Chin KC, Cheng YC, Sun JT, Ou CY, Hu CH, Tsai MC, Ma MH, Chiang WC, Chen AY.   +8 more
europepmc   +1 more source

Trace Li Pre‐Doping of Activated Carbon Cathode Enabling Accelerated Li‐Ion Transport for High‐Power Lithium‐Ion Capacitors

Advanced Science, EarlyView.
Trace‐level Li pre‐doping on activated carbon cathodes is demonstrated to significantly enhance Li‐ion transport and high‐rate performance in lithium‐ion capacitors. An ultrathin Li2CO3 interfacial layer, formed through controlled thermal conversion, facilitates rapid ion transport without pore blockage.
Kyungmin Do, Jihyeon Ryu, Dong Gyun Im, Seong‐Yong Kim, Tae‐Hyun Kwon, Byeong Guk Kim, Seojin Jeon, Woosun Jang, Myoung Joon Hwang, Ki‐Hun Nam, Seung Yol Jeong, Ick‐Jun Kim, Seungwook Eom, Jaeik Hyun, Sunhye Yang   +14 more
wiley   +1 more source

Criteria codes for unrecognized stroke/TIA patients by Emergency Medical Services dispatchers in Copenhagen, Denmark

BMC Emergency Medicine
Background Early diagnosis is essential in stroke treatment. Medical dispatchers play a key role in ensuring quick assessment, transport, and treatment of stroke patients by recognizing stroke symptoms.
Philip Busch Andreasen, Jonathan Wenstrup, Stig Nikolaj Fasmer Blomberg, Christina Kruuse, Helle Collatz Christensen   +4 more
doaj   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source