Results 81 to 90 of about 8,170 (220)

The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset

Advanced Science, EarlyView.
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng, Hua Wang, Li Zhang, Shiping Li, Yuan Yuan, Mengting Tian, Yi Qu, Junjie Ying, Meicen Zhou, Yong Hu, Jinglan Huang, Rong Zou, Fengyan Zhao, Xiaojuan Su, Qian Liu, Yan He, Jinxing Feng, Weimin Huang, Ying Luo, Zhemin Zhou, Wei Shen, Dezhi Mu, Shaopu Wang   +22 more
wiley   +1 more source

The potential of new prediction models for emergency medical dispatch prioritisation of patients with chest pain: a cohort study. [PDF]

Scand J Trauma Resusc Emerg Med, 2022
Wibring K, Lingman M, Herlitz J, Bång A.   +3 more
europepmc   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Correlation between the accuracy of the emergency response centre’s urgency assessment and emergency medical services non-conveyance: a retrospective register-based study in Finland

BMC Emergency Medicine
Background In modern emergency medical services (EMS), ambulances increasingly focus on examining and treating the patient at the scene. This has led to increased levels of non-conveyance. In Finland, for instance, approximately 40% of EMS dispatches end
Tomi Salminen, Kaius Kaartinen, Mira Palonen, Piritta Setälä, Eija Paavilainen, Sanna Hoppu   +5 more
doaj   +1 more source

High‐Performance Zinc–Bromine Rechargeable Batteries Enabled by In‐Situ Formed Solid Electrolyte Interphase

Advanced Science, EarlyView.
A hydrophobic surface coating enables the in‐situ formation of a zinc fluoride‐rich solid electrolyte interphase (SEI) in zinc–bromine batteries. This SEI suppresses dendrite formation and water‐induced side reactions, leading to uniform zinc deposition, reduced voltage hysteresis, and extended cycle life. The strategy offers a scalable pathway to high‐
Norah S. Alghamdi, Xiyue Peng, Xingchen Yang, Shengyong Gao, Yongxin Huang, Shuangbin Zhang, Tong'en Lin, Cheng Zhang, Ian R. Gentle, Lianzhou Wang, Bin Luo   +10 more
wiley   +1 more source

Feedback on emergency medical dispatching – the ambulance crew experience of a computer based feedback system [PDF]

, 2009
Veronica Lindström, Ann‐Charlotte Falk, Maaret Castrén   +2 more
openalex   +1 more source

Enhanced One‐Pot Dual‐CRISPR‐Based Assay Lyophilized on a 3D‐Printed Disc for Field‐Deployable Multiplex Bacteria Detection

Advanced Science, EarlyView.
An enhanced one‐pot, helicase‐assisted recombinase polymerase amplification (hRPA)‐combined, dual‐CRISPR/uAsCas12a assay is developed and lyophilized on a 3D‐printed microfluidic disc to achieve field‐deployable multiplex bacteria detection. Abstract One‐pot CRISPR‐based detection combining recombinase polymerase amplification (RPA) enables rapid and ...
Yuqing Shen, Bo Lu, Biao Ma, Xiong Ding
wiley   +1 more source

The perspectives of Swedish registered nurses about managing difficult calls to emergency medical dispatch centres: a qualitative descriptive study. [PDF]

BMC Nurs, 2021
Holmström IK, Kaminsky E, Lindberg Y, Spangler D, Winblad U.   +4 more
europepmc   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

Aging as a Loss of Goal‐Directedness: An Evolutionary Simulation and Analysis Unifying Regeneration with Anatomical Rejuvenation

Advanced Science, EarlyView.
The paper proposes that the root cause of aging is the loss of anatomical goal‐directedness after development. Using evolutionary neural cellular automata simulations, the authors show that after the organism has reached its developmental homeostatic setpoint (the adult morphology), the absence of target state to pursue leads to a drifting anatomical ...
Léo Pio‐Lopez, Benedikt Hartl, Michael Levin   +2 more
wiley   +1 more source