Results 161 to 170 of about 10,370,996 (312)

Lactylation‐Mediated HER2 Stabilization Promotes Trastuzumab Resistance in Gastric Cancer

Advanced Science, EarlyView.
Warburg effect‐derived lactate drives HER2 lactylation and trastuzumab resistance. Mechanistically, AARS1‐mediated lactylation stabilizes HER2 by inhibiting USP11‐dependent degradation and concurrently promotes HER2‐EGFR interaction. Importantly, inhibiting HER2 lactylation resensitizes gastric cancer cells to trastuzumab.
Meng Qian, Tongguan Tian, Zhenxiang Wang, Huihui Sun, Ming Zong, Ying Chen, Jie Xiong, Ye Chen, Zhiqian Hu, Tianming Li, Yanping Xu, Shuchang Xu   +11 more
wiley   +1 more source

Other title: State of Connecticut Department of Emergency Services and Public Protection; Other title: Emergency Services and Public Protection

, 2017
Updated irregularly; Began in 2012.; Title from home page (publisher's Web site, viewed Feb. 9, 2012).; At head of title: State of Connecticut.; Harvested from the web on 5/8/17Official website of the Connecticut Department of Emergency Services and ...

core  

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Kansas emergency medical services : state plan [1973]

, 1973
"April 1973."Introduction -- State Organization for EMS Planning and Implementation -- Planning Information -- EMS Standards -- Program Implementation and Objectives ...
Governor's Commission on Emergency Medical Services
core  

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Toronto Emergency Medical Services and SARS

Emerging Infectious Diseases, 2004
Alexis Silverman, Andrew Simor, Mona R. Loutfy   +2 more
doaj   +1 more source

Cyberwarfare Beyond the Hospital: Emergency Medical Services as a Critical Infrastructure Vulnerability. [PDF]

Open Access Emerg Med
Gordon KR, Denton EE, Talledo C, Mathew G, Nicholson J, Ventura CAI.   +5 more
europepmc   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

Advanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu, Xingyun Liu, Fangzhou Wang, Huili Ren, Chaojun Zhang, Ziyu Ren, Zunqi Liu, Jing Li   +7 more
wiley   +1 more source

Other title: State of Connecticut Department of Emergency Services and Public Protection; Other title: Emergency Services and Public Protection

, 2013
Updated irregularly; Began in 2012.; Title from home page (publisher's Web site, viewed Feb. 9, 2012).; At head of title: State of Connecticut .; Harvested from the web on 2/25/13Official website of the Connecticut Department of Emergency Services and ...

core  

Forecasting and Capacity Planning in Prehospital Emergency Medical Services: The Case of Ankara. [PDF]

Int J Health Plann Manage
Erbay E, Akyürek ÇE.
europepmc   +1 more source