Results 151 to 160 of about 344,311 (256)

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

open access: yesAdvanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra   +6 more
wiley   +1 more source

Renal screening sonography-A comparative study in a Portuguese basic emergency service. [PDF]

open access: yesJ Med Radiat Sci
Miravent S   +9 more
europepmc   +1 more source

An online mental health informed physical activity intervention for emergency service workers and their families: A stepped-wedge trial. [PDF]

open access: yesDigit Health, 2023
McKeon G   +6 more
europepmc   +1 more source

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

open access: yesAdvanced Science, EarlyView.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner   +14 more
wiley   +1 more source

Pre-hospital Emergency Service Challenges in the Face of the COVID-19 Pandemic in Iran. [PDF]

open access: yesDisaster Med Public Health Prep, 2022
Heidari M   +4 more
europepmc   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

The Impact of the COVID-19 Pandemic on the Dental Emergency Service from Oradea, Romania: A Retrospective Study. [PDF]

open access: yesHealthcare (Basel), 2022
Moca AE   +5 more
europepmc   +1 more source

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