Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
A Task Complexity Analysis Method to Study the Emergency Situation under Automated Metro System. [PDF]
Niu K +6 more
europepmc +1 more source
The Education on Emergency Response and Disaster for Junior High School Students of Surakarta [PDF]
Emergency is abnormal and dangerous situations that threaten or require quick action to control, fixed and restored it to the safety condition. Most parts of Indonesia territory are vulnerable to disasters, whether natural and non-natural disasters or ...
Setyawan, H. (Haris) +1 more
core
Many-particle simulation of the evacuation process from a room without visibility
We study the evacuation process from a smoky room by means of experiments and simulations. People in a dark or smoky room are mimicked by ``blind'' students wearing eye masks.
Helbing, Dirk +2 more
core +1 more source
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He +10 more
wiley +1 more source
Second wave of COVID-19: emergency situation in India. [PDF]
Kumar S.
europepmc +1 more source
Challenges in Collaborative HRI for Remote Robot Teams [PDF]
Collaboration between human supervisors and remote teams of robots is highly challenging, particularly in high-stakes, distant, hazardous locations, such as off-shore energy platforms.
Ahmad, Muneeb +8 more
core +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
ANALYSIS AND ASSESSMENT OF NPP EXPOSURE TO NATURAL TECHNOGENIC EMERGENCY SITUATIONS
On the basis of the gathered statistics on the NPP accidents and earthquakes all over the world, the correlative relationship (according to Pearson criterion) between the NPP accident risks and natural technogenic ES risks effecting the stability and ...
Yury I. Bulygin +3 more
doaj
Cognitive Aid for Anesthetic Preparation in An Emergency Situation: A Simulation-Based Study. [PDF]
Rineau E +7 more
europepmc +1 more source

