Results 111 to 120 of about 407,798 (310)
Emergent participant interaction
, 2012 Emergence has the potential to effect complex, creative or open-ended interactions and novel game-play. We report on research into an emergent interactive system.
Edmonds, Ernest A. +8 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
3D skyrmion strings and their melting dynamics revealed via scalar-field electron tomography
Communications MaterialsTwo-dimensional skyrmion, a topological spin texture, has been extensively investigated in non-centrosymmetric magnets. It is thermodynamically stable in bulk materials and can extend perpendicularly to the spin-rotating plane, forming the three ...
Xiuzhen Yu +9 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
An emergent wall following behaviour to escape local minima for swarms of agents
, 2008 Natural examples of emergent behaviour, in groups due to interactions among the group's individuals, are numerous. Our aim, in this paper, is to use complex emergent behaviour among agents that interact via pair-wise attractive and repulsive potentials ...
Abdel Wahid, Mohamed Hussien Mabrouk +3 more
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Cognitive control: componential or emergent?
, 2010 The past twenty-five years have witnessed an increasing awareness of the importance of cognitive control in the regulation of complex behavior. It now sits alongside attention, memory, language and thinking as a distinct domain within cognitive ...
Richard P. Cooper, Cooper, Richard P.
core +1 more source
Emerging Sight, Emerging Blindness
, 2012 This essay covers two main topics: the role of the “double vi-sion” of the sight/nonsight of blinking in selected fiction of Neil Gaiman and China Miéville, and an examination of the role of blindness and sight surrounding “Molyneux’s question.” In Gaiman’s work “double vision” functions as a synchronic representation of diachronic events.
openaire +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Interpretation of Emergent Situations in Conceptual Design
, 2012 Interpretation process is usually oriented to some purposes, e.g., for identifi cation, for explanation, for inference, for translation, etc. By the interpretation in this paper is understood not only the explanation of a confi guration of signs (symbols)
J. Jura, J. BÌla
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