Results 91 to 100 of about 509,863 (283)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Pest Des Petits Ruminants in Eastern Europe: An Emerging Threat

Acta Veterinaria
Peste des petits ruminants is a highly contagious viral disease affecting small ruminants, with significant socioeconomic impact, particularly in regions with extensive livestock farming.
Răţoi Ioana Alexandra, Oşlobanu Luanda Elena, Porea Daniela, Maftei Daniel Narcis, Kureljušić Jasna, Milićević Vesna, Kureljušić Branislav, Vasić Ana   +7 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Emergent Esophagectomy in Patients with Esophageal Malignancy Is Associated with Higher Rates of Perioperative Complications but No Independent Impact on Short-Term Mortality

Journal of Chest Surgery
Background: Data on perioperative outcomes of emergent versus elective resection in esophageal cancer patients requiring esophagectomy are lacking.
Yahya Alwatari, Devon C. Freudenberger, Jad Khoraki, Lena Bless, Riley Payne, Walker A. Julliard, Rachit D. Shah, Carlos A. Puig   +7 more
doaj   +1 more source

A Narrative-Developmental Approach to Early Emotions

Forum: Qualitative Social Research, 2001
Over the past decades a great deal of attention has been dedicated to the broadening and diversification of the notion of narratives, which lead to a variety of models for narrative analysis and encouraged some to speak of a "narratological renaissance" (
Andréa P.F. Pantoja
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Emerging Sight, Emerging Blindness

, 2012
This essay covers two main topics: the role of the “double vi-sion” of the sight/nonsight of blinking in selected fiction of Neil Gaiman and China Miéville, and an examination of the role of blindness and sight surrounding “Molyneux’s question.” In Gaiman’s work “double vision” functions as a synchronic representation of diachronic events.
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

3D skyrmion strings and their melting dynamics revealed via scalar-field electron tomography

Communications Materials
Two-dimensional skyrmion, a topological spin texture, has been extensively investigated in non-centrosymmetric magnets. It is thermodynamically stable in bulk materials and can extend perpendicularly to the spin-rotating plane, forming the three ...
Xiuzhen Yu, Nobuto Nakanishi, Yi-Ling Chiew, Yizhou Liu, Kiyomi Nakajima, Naoya Kanazawa, Kosuke Karube, Yasujiro Taguchi, Naoto Nagaosa, Yoshinori Tokura   +9 more
doaj   +1 more source