Results 141 to 150 of about 509,863 (283)

Spatiotemporal Variations of Temperature, Oxygen, and Salinity in a Typical Constructed Wetland for Source Water Protection in a Plain River Network. [PDF]

Water Environ Res
Zhai W, Sun J, Wang L, Xu J, Fu Q, Wang W.   +5 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Machine Perfusion as a Temporal and Resuscitative Bridge in Emergent Renal Autotransplantation: A Novel Case Report. [PDF]

Am J Case Rep
Johnson M, Archie W, Mylarapu N, Vrochides D, Baimas-George M, Casingal V.   +5 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Interpretation of Emergent Situations in Conceptual Design

, 2012
Interpretation process is usually oriented to some purposes, e.g., for identifi cation, for explanation, for inference, for translation, etc. By the interpretation in this paper is understood not only the explanation of a confi guration of signs (symbols)
J. Jura, J. BÌla
core  

Rapid detection of treatment-emergent resistance to bedaquiline and pretomanid in <i>Mycobacterium tuberculosis</i> using TM4::<i>GeNL</i> reporter mycobacteriophages. [PDF]

Microbiol Spectr
Ngema SL, Rajagopalan S, Perumal R, Moodley S, Guzman KJ, Steyn AJC, Jacobs WR, Naidoo K, O'Donnell M, Larsen MH.   +9 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

When Time Matters in Aortic Stenosis: Can Transcatheter Aortic Valve Replacement Make a Difference in Non-Elective Cases? [PDF]

Rev Cardiovasc Med
Villa Etchegoyen C, Chollet L, Ahmed M, Bilauca C, Farina JM, Pereyra M, Scalia IG, Razaghi M, Abdelfattah FE, Awad K, Hafez A, Ahmed S, Ayoub C, Alsidawi S, Sweeney JP, Lester SJ, Lee KS, Fortuin D, Sell-Dottin KA, Arsanjani R.   +19 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Theory and practice in biomedical informatics: a framework for discovery. [PDF]

J Am Med Inform Assoc
Stead WW, Aliferis CF, Bastarache L, Lorenzi NM, Ed Hammond W.   +4 more
europepmc   +1 more source