Results 191 to 200 of about 1,561,128 (291)

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation. [PDF]

Pharmaceutics, 2021
Schijns V, Majhen D, van der Ley P, Thakur A, Summerfield A, Berisio R, Nativi C, Fernández-Tejada A, Alvarez-Dominguez C, Gizurarson S, Zamyatina A, Molinaro A, Rosano C, Jakopin Ž, Gursel I, McClean S.   +15 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Editorial: RNA vaccines for prevalent and newly emerging diseases. [PDF]

Front Immunol
López-Camacho C, Alameh MG, Peer D, Culis P.   +3 more
europepmc   +1 more source

Contributions of the international plant science community to the fight against infectious diseases in humans-part 2: Affordable drugs in edible plants for endemic and re-emerging diseases. [PDF]

Plant Biotechnol J, 2021
He W, Baysal C, Lobato Gómez M, Huang X, Alvarez D, Zhu C, Armario-Najera V, Blanco Perera A, Cerda Bennaser P, Saba-Mayoral A, Sobrino-Mengual G, Vargheese A, Abranches R, Alexandra Abreu I, Balamurugan S, Bock R, Buyel JF, da Cunha NB, Daniell H, Faller R, Folgado A, Gowtham I, Häkkinen ST, Kumar S, Sathish Kumar R, Lacorte C, Lomonossoff GP, Luís IM, K-C Ma J, McDonald KA, Murad A, Nandi S, O'Keef B, Parthiban S, Paul MJ, Ponndorf D, Rech E, Rodrigues JCM, Ruf S, Schillberg S, Schwestka J, Shah PS, Singh R, Stoger E, Twyman RM, Varghese IP, Vianna GR, Webster G, Wilbers RHP, Christou P, Oksman-Caldentey KM, Capell T.   +51 more
europepmc   +1 more source

Surveillance of emerging diseases: challenges and contradictions [PDF]

, 2018
Roger, François
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Editorial: Wildlife parasitology: emerging diseases and neglected parasites. [PDF]

Front Vet Sci
Deak G, Germitsch N, Rojas A, Sazmand A.
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Emerging Diseases in Spain Strawberry Crops: Neopestalotiopsis Leaf and Crown Rot and Fusarium Wilt. [PDF]

Plants (Basel)
Avilés M, Pastrana AM, Borrero C.
europepmc   +1 more source

Units for vigilance of emerging diseases based on wastewater treatment plants (WWTP-UVED). [PDF]

Microb Biotechnol, 2020
Barros-Rodríguez A, Manzanera M.
europepmc   +1 more source