Results 21 to 30 of about 1,561,128 (291)

Emerging infectious diseases [PDF]

Medicine, 2014
Resumen El espectro de patógenos humanos y las enfermedades infecciosas que causan está cambiando continuamente a través de la evolución y los cambios en la forma en que las poblaciones humanas interactúan con su entorno y entre sí. Los nuevos patógenos humanos surgen con mayor frecuencia de un reservorio animal, lo que enfatiza el papel central que ...
openaire   +6 more sources

Serological evidence and experimental infection of cynomolgus macaques with pteropine orthoreovirus reveal monkeys as potential hosts for transmission to humans

Emerging Microbes and Infections, 2019
Pteropine orthoreoviruses (PRV) are emerging bat-borne viruses with proven zoonotic transmission. We recently demonstrated human exposure to PRV in Singapore, which together with previous reports from Malaysia and Vietnam suggest that human infection of ...
Chee Wah Tan, Kevin Wittwer, Xiao Fang Lim, Anna Uehara, Shailendra Mani, Lin-Fa Wang, Danielle E. Anderson   +6 more
doaj   +1 more source

High flavivirus structural plasticity demonstrated by a non-spherical morphological variant

Nature Communications, 2020
Dengue (DENV) and Zika (ZIKV) viruses normally display as smooth spherical particles, while DENV can also become bumpy-surfaced, resulting in immune evasion. Here, Morrone et al. report DENV and ZIKV infectious club-shaped particles (clubSP) that display
Seamus R. Morrone, Valerie S. Y. Chew, Xin-Ni Lim, Thiam-Seng Ng, Victor A. Kostyuchenko, Shuijun Zhang, Melissa Wirawan, Pau-Ling Chew, Jaime Lee, Joanne L. Tan, Jiaqi Wang, Ter Yong Tan, Jian Shi, Gavin Screaton, Marc C. Morais, Shee-Mei Lok   +15 more
doaj   +1 more source

Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccine

npj Vaccines, 2022
Remarkable potency has been demonstrated for mRNA vaccines in reducing the global burden of the ongoing COVID-19 pandemic. An alternative form of the mRNA vaccine is the self-amplifying mRNA (sa-mRNA) vaccine, which encodes an alphavirus replicase that ...
Eugenia Z. Ong, Jia Xin Yee, Justin S. G. Ooi, Ayesa Syenina, Ruklanthi de Alwis, Shiwei Chen, Jean X. Y. Sim, Shirin Kalimuddin, Yan Shan Leong, Yvonne F. Z. Chan, Rose Sekulovich, Brian M. Sullivan, Kelly Lindert, Sean B. Sullivan, Pad Chivukula, Steven G. Hughes, Jenny G. Low, Eng Eong Ooi, Kuan Rong Chan   +18 more
doaj   +1 more source

Spike-Independent Infection of Human Coronavirus 229E in Bat Cells

Microbiology Spectrum, 2023
Bats are the reservoir for numerous human pathogens, including coronaviruses. Despite many coronaviruses having descended from bat ancestors, little is known about virus-host interactions and broader evolutionary history involving bats.
Marcus G. Mah, Martin Linster, Dolyce H. W. Low, Yan Zhuang, Jayanthi Jayakumar, Firdaus Samsudin, Foong Ying Wong, Peter J. Bond, Ian H. Mendenhall, Yvonne C. F. Su, Gavin J. D. Smith   +10 more
doaj   +1 more source

Zika virus and the never-ending story of emerging pathogens and transfusion medicine [PDF]

, 2016
In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses.
Grazzini, Giuliano, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +4 more
core   +1 more source

SARS-CoV-2 genomic and subgenomic RNAs in diagnostic samples are not an indicator of active replication

Nature Communications, 2020
During SARS-CoV-2 replication subgenomic RNAs (sgRNA) are transcribed and subsequently translated into viral proteins. Here, Alexandersen et al. provide evidence that sgRNA is not necessarily an indicator for active viral replication, but can be detected
Soren Alexandersen, Anthony Chamings, Tarka Raj Bhatta   +2 more
doaj   +1 more source

Understanding the failure of a behavior change intervention to reduce risk behaviors for avian influenza transmission among backyard poultry raisers in rural Bangladesh: a focused ethnography

BMC Public Health, 2016
Background The spread of the highly pathogenic avian influenza (HPAI) H5N1 virus among poultry and humans has raised global concerns and has motivated government and public health organizations to initiate interventions to prevent the transmission of ...
Nadia Ali Rimi, Rebeca Sultana, Kazi Ishtiak-Ahmed, Md Zahidur Rahman, Marufa Hasin, M. Saiful Islam, Eduardo Azziz-Baumgartner, Nazmun Nahar, Emily S. Gurley, Stephen P. Luby   +9 more
doaj   +1 more source

Twenty-two years of dengue outbreaks in Bangladesh: epidemiology, clinical spectrum, serotypes, and future disease risks

Tropical Medicine and Health, 2023
Dengue is the most rapidly spreading mosquito-borne disease and has become a major public health threat, particularly for tropical and subtropical countries including Bangladesh. This comprehensive review aims to summarize the overall scenario of dengue,
Mohammad Sorowar Hossain, Abdullah Al Noman, SM Abdullah Al Mamun, Abdullah Al Mosabbir   +3 more
doaj   +1 more source

The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases [PDF]

, 2014
Copyright © 2014 Al-Mahdawi, Anjomani Virmouni and Pook. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Al-Mahdawi, S, Pook, MA, Virmouni, SA
core   +1 more source