Results 61 to 70 of about 822,085 (315)

Bone marrow-derived mesenchymal stem cells attenuate pulmonary inflammation and lung damage caused by highly pathogenic avian influenza A/H5N1 virus in BALB/c mice

BMC Infectious Diseases, 2020
Background The highly pathogenic avian influenza A/H5N1 virus is one of the causative agents of acute lung injury (ALI) with high mortality rate. Studies on therapeutic administration of bone marrow-derived mesenchymal stem cells (MSCs) in ALI caused by ...
Resti Yudhawati, Muhammad Amin, Fedik A. Rantam, Rima R. Prasetya, Jezzy R. Dewantari, Aldise M. Nastri, Emmanuel D. Poetranto, Laksmi Wulandari, Maria I. Lusida, Soetjipto Koesnowidagdo, Gatot Soegiarto, Yohko K. Shimizu, Yasuko Mori, Kazufumi Shimizu   +13 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Antimalarial Efficacy of Ethanol Extract of Bridelia micrantha Stem Bark against Plasmodium berghei-Infected Mice

Journal of Parasitology Research
Background. The spread of drug resistance is a significant issue, particularly in endemic countries with limited resources. The aim of this study was to evaluate antimalarial and antioxidant activity of B.
Tako Djimefo Alex Kevin, Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Tientcheu Noutong Jemimah Sandra, Mounvera Abdel Azizi, Ngouyamsa Nsapkain Aboubakar Sidiki, Gamago Nkadeu Guy-Armand, Mbohou Nchetnkou Christian, Essangui Same Estelle Géraldine, Tankoua-Tchounda Roméo, Vincent Khan Payne, Lehman Léopold Gustave   +11 more
doaj   +1 more source

Emerging infectious diseases [PDF]

Journal of Clinical Investigation, 2004
Human population growth, technological advances, and changing social behaviors lead to the selection of new microbial pathogens. Antimicrobial drugs, vaccines, diagnostics, and treatments for emerging infectious diseases must be developed. The selective forces that drive the emergence of new infectious diseases, and the implications for our survival ...
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

National Center for Emerging and Zoonotic Infectious Diseases [PDF]

The National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) aims to detect, prevent, and control infectious diseases from spreading, whether they are naturally occurring, unintentional, or the result of terrorism. The center focuses on new,

core   +2 more sources

Emerging infectious diseases [PDF]

Medicine, 2014
Resumen El espectro de patógenos humanos y las enfermedades infecciosas que causan está cambiando continuamente a través de la evolución y los cambios en la forma en que las poblaciones humanas interactúan con su entorno y entre sí. Los nuevos patógenos humanos surgen con mayor frecuencia de un reservorio animal, lo que enfatiza el papel central que ...
openaire   +6 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Research contributes to addressing emerging infectious diseases

, 2009
This is a one-page backgrounder on the Asian Partnership for Emerging Infectious Diseases Research (APEIR). APEIR focuses on policy-relevant research that addresses the wider determinants and consequences of Emerging Infectious Diseases (EIDs).
Asian Partnership on Emerging Infectious Diseases Research (APEIR)
core  

Potential Role of ACE Polymorphisms in Severe Malaria: A Case Report

Case Reports in Infectious Diseases
This case aims to contribute to the debate about the role of ACE polymorphisms in malaria severity. Comprehensive studies are warranted to explore the genetic landscape in malaria-endemic regions and its implications for personalized treatment strategies.
Raffaella Pisapia, Andrea Pomicino, Giuseppina Minei, Isabella Iadevito, Alessandro Perrella   +4 more
doaj   +1 more source