Results 41 to 50 of about 76,691 (265)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Integrating Digital Twins into Smart Warehousing: A Practice-Based View Framework for Identifying and Prioritizing Critical Success Factors

Logistics
Background. Smart warehousing increasingly relies on digital twin technologies to enhance operational efficiency, real-time visibility, and decision-making in logistics systems.
Sadia Samar Ali, Jose Antonio Marmolejo-Saucedo, Rosario Landa Piedra, Gerhard-Wilhelm Weber   +3 more
doaj   +1 more source

Export performance in South America: do intangibles affect firms’ performance in developing countries such as Peru? [PDF]

RAE: Revista de Administração de Empresas, 2021
This study is one of the first empirical studies on intellectual capital (IC) in South American textile exporting companies. Using the resources and capabilities approach, we examine how certain intangibles can provide competitive advantages.
Carlos Del Castillo Guardamino, José Ventura Egoávil   +1 more
doaj  

Convergence in Large Emerging Economies

Procedia - Social and Behavioral Sciences, 2014
AbstractThis study aims at investigating convergence processes in a number of large emerging economies that have increased their share in world output. We consider an extended version of BRICs: Brazil, Russia, India and China, plus Indonesia, Mexico, South Africa, South Korea and Turkey.
Akarçay Gürbüz, Ayça, GÜRBÜZ, ZEHRA YEŞİM   +1 more
openaire   +3 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A partnership-based model for embedding employability in urban planning education

Urban, Planning and Transport Research, 2016
This paper proposes a partnership-based model for embedding employability in urban planning education. The model is based on the author’s experiences of implementing an international project which supported the development of employability skills in ...
Neale Blair, Mtafu Manda
doaj   +1 more source

Impact of ownership type and firm size on organizational culture and on the organizational culture-effectiveness linkage

Journal of Business Economics and Management, 2013
This paper aims to extend the extant (primarily Western) organizational culture literature to emerging economies by explicitly incorporating two key contextual variables-ownership type and firm size into organizational culture model.
Kaisheng Zeng, Xiaohui Luo
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source