Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Characterising COVID-19 school and childcare outbreaks in Canada in 2021: a surveillance study
Background In January 2021, the Public Health Agency of Canada launched the Canadian COVID-19 Outbreak Surveillance System to monitor outbreaks by setting. Schools and childcare centres were identified as settings of interest, as children play a key role
Kaitlin Patterson +5 more
doaj +1 more source
Viral Innate Immune Evasion and the Pathogenesis of Emerging RNA Virus Infections
Positive-sense single-stranded RNA (+ssRNA) viruses comprise many (re-)emerging human pathogens that pose a public health problem. Our innate immune system and, in particular, the interferon response form the important first line of defence against these
Tessa Nelemans, M. Kikkert
semanticscholar +1 more source
Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network Group A Streptococcus, 2020 [PDF]
Dataset version: Jul 2022 Final run: Sep 20, 2022Citation: Centers for Disease Control and Prevention. 2020. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group A Streptococcus, 2020.Publication date from document ...
core
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Streptococcus pneumoniae, 2018 [PDF]
Citation: Centers for Disease Control and Prevention. 2018. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae, 2018.
core
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Group B Streptococcus, 2019 [PDF]
Citation: Centers for Disease Control and Prevention. 2019. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group B Streptococcus, 2019.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Vaccine Strategies Against RNA Viruses: Current Advances and Future Directions
The development of vaccines against RNA viruses has undergone a rapid evolution in recent years, particularly driven by the COVID-19 pandemic. This review examines the key roles that RNA viruses, with their high mutation rates and zoonotic potential ...
Kuei-Ching Hsiung +3 more
doaj +1 more source

