Results 101 to 110 of about 9,693,931 (354)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Characterising COVID-19 school and childcare outbreaks in Canada in 2021: a surveillance study

open access: yesBMJ Public Health
Background In January 2021, the Public Health Agency of Canada launched the Canadian COVID-19 Outbreak Surveillance System to monitor outbreaks by setting. Schools and childcare centres were identified as settings of interest, as children play a key role
Kaitlin Patterson   +5 more
doaj   +1 more source

Viral Innate Immune Evasion and the Pathogenesis of Emerging RNA Virus Infections

open access: yesViruses, 2019
Positive-sense single-stranded RNA (+ssRNA) viruses comprise many (re-)emerging human pathogens that pose a public health problem. Our innate immune system and, in particular, the interferon response form the important first line of defence against these
Tessa Nelemans, M. Kikkert
semanticscholar   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network Group A Streptococcus, 2020 [PDF]

open access: yes
Dataset version: Jul 2022 Final run: Sep 20, 2022Citation: Centers for Disease Control and Prevention. 2020. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group A Streptococcus, 2020.Publication date from document ...

core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Streptococcus pneumoniae, 2018 [PDF]

open access: yes
Citation: Centers for Disease Control and Prevention. 2018. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae, 2018.

core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Group B Streptococcus, 2019 [PDF]

open access: yes
Citation: Centers for Disease Control and Prevention. 2019. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group B Streptococcus, 2019.

core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Vaccine Strategies Against RNA Viruses: Current Advances and Future Directions

open access: yesVaccines
The development of vaccines against RNA viruses has undergone a rapid evolution in recent years, particularly driven by the COVID-19 pandemic. This review examines the key roles that RNA viruses, with their high mutation rates and zoonotic potential ...
Kuei-Ching Hsiung   +3 more
doaj   +1 more source

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