Results 121 to 130 of about 9,693,931 (354)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Future science prize goes to EMI editorial board members and the science of emerging infections

Emerging Microbes and Infections, 2022
Shan Lu, Yu-mei Wen
doaj   +1 more source

Emerging respiratory infections: The infectious disease pathology of SARS, MERS, pandemic influenza, and Legionella

Seminars in diagnostic pathology, 2019
Lower respiratory infections remain one of the top global causes of death and the emergence of new diseases continues to be a concern. In the first two decades of the 21st century, we have born witness to the emergence of newly recognized coronaviruses ...
B. T. Bradley, A. Bryan
semanticscholar   +1 more source

Active Bacterial Core Surveillance (ABCs) report : Emerging Infections Program Network : Neisseria meningitidis, 2019 [PDF]

Citation: Centers for Disease Control and Prevention. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Neisseria meningitidis, 2019. www.cdc.gov/abcs/downloads/NMEN_Surveillance_Report_2019.pdfPublication date from document

core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Incidence, viral etiology, and risk factors of wheezing in children under two years of age: findings from a low-income urban community in Dhaka, Bangladesh

BMC Pulmonary Medicine
Background The burden of early childhood wheezing in Bangladesh remains poorly characterised, despite infants’ exposure to viral pathogens and substantial particulate pollution.
Homayra Rahman Shoshi, Ashrak Shad Pyash, Md Abdullah Al Jubayer Biswas, Md. Altaf Ahmed Riaj, Mustafizur Rahman, Rashidul Haque, William Petri, Fahmida Chowdhury, Md. Zakiul Hassan   +8 more
doaj   +1 more source

Lyme disease in UK primary care: a knowledge, attitude, and practice survey

BJGP Open
Background: Lyme disease (LD) cases in the UK most commonly present within the primary care setting. Despite an upward trend of incidence, little is known regarding GP experience with diagnosis and treatment.
Lucy Delaney, Amanda Semper, Neil French, John SP Tulloch   +3 more
doaj   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network Group B Streptococcus, 2020 [PDF]

Dataset version: Jul 2022; Final run: Sep 20, 2022Citation: Centers for Disease Control and Prevention. 2020. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group B Streptococcus, 2020.

core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Understanding the landscape of carbapenemase-producing organisms (CPOs), and spotlighting opportunities for control in England

Infection Prevention in Practice
SUMMARY: Carbapenemase-producing organisms (CPOs) are an increasing global public health threat for which there are limited effective and affordable therapeutic options. The rise in the incidence of CPO infections and colonisations recorded across the UK
Akaninyene Otu, Jacquelyn McCormick, Katherine L. Henderson, Alice Ledda, Danièle Meunier, Bharat Patel, Colin S. Brown, Susie Singleton, Emily L. Mason, Jasmin Islam, Ginny Moore, Katie L. Hopkins, Dakshika Jeyaratnam   +12 more
doaj   +1 more source