Results 61 to 70 of about 9,693,931 (354)

The effect of chemical fixation with paraformaldehyde, glutardialdehyde or methanol on immunofluorescence staining of neutrophils and neutrophil extracellular traps

Innate Immunity
The formation of neutrophil extracellular traps (NETs) is known as an important part of the innate immune response. Still, some mechanisms regarding their formation and role during a disease are not completely understood yet.
Veronika Pilchová, Armina Richter, Marita Meurer, Claudia Schulz, Maren von Köckritz-Blickwede   +4 more
doaj   +1 more source

Preparing for emerging infections [PDF]

Nature, 1994
New infectious diseases continue to emerge, yet there is no clear strategy for managing them. A model response should be devised in the light of past events such as the recent US outbreak of a previously unknown hantavirus.
openaire   +2 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

EMERGING INFECTIONS

Science Translational Medicine, 2018
The Zika virus (ZIKV) epidemic is associated with fetal brain lesions and other serious birth defects classified as congenital ZIKV syndrome. Postnatal ZIKV infection in infants and children has been reported; however, data on brain anatomy, function ...
M. Mavigner, J. Raper, Z. Kovacs-Balint, S. Gumber, Justin T. O'Neal, S. Bhaumik, Xiao-Dong Zhang, J. Habib, C. Mattingly, C. McDonald, Victoria Avanzato, M. Burke, D. Magnani, Varian K. Bailey, David I. Watkins, T. Vanderford, D. Fair, E. Earl, E. Feczko, M. Styner, S. Jean, Joyce K. Cohen, Guido Silvestri, R. P. Johnson, David H. O'Connor, J. Wrammert, M. Suthar, M. Sanchez, M. C. Alvarado, A. Chahroudi   +29 more
semanticscholar   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

STAT1 signaling controls cholesterol metabolism in epithelial cells and RSV-induced syncytia formation

npj Viruses
Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infections, leading to significant morbidity, hospitalizations, and mortality among high-risk populations.
Ayse Agac, Martin Ludlow, Marie-Christin Knittler, Albert D.M.E. Osterhaus, Guus F. Rimmelzwaan, Robert Meineke   +5 more
doaj   +1 more source

Activation of type I interferon antiviral response in human neural stem cells

Stem Cell Research & Therapy, 2019
Background Neural stem cells (NSCs) residing in the central nervous system play an important role in neurogenesis. Several viruses can infect these neural progenitors and cause severe neurological diseases.
Jhao-Yin Lin, Rei-Lin Kuo, Hsing-I Huang
doaj   +1 more source

Improving Antimicrobial Stewardship by Antibiotic Allergy Delabeling: Evaluation of Knowledge, Attitude, and Practices Throughout the Emerging Infections Network

Open Forum Infectious Diseases, 2016
Antibiotic allergy testing (AAT) practices of Emerging Infections Network infectious disease physicians were surveyed. Although AAT was perceived to be necessary for removal of inappropriate or unnecessary allergy labels, there was limited access to any ...
J. Trubiano, S. Beekmann, L. Worth, P. Polgreen, K. Thursky, M. Slavin, M. Grayson, E. Phillips   +7 more
semanticscholar   +1 more source

Therapeutic potential of resveratrol against emerging respiratory viral infections.

Pharmacology and Therapeutics, 2020
Resveratrol has been widely studied for its therapeutic potential due to its antioxidant, anti-inflammatory and anti-microbial properties. In particular, resveratrol has shown promising antiviral activity against numerous viruses responsible for severe ...
S. Filardo, M. Di Pietro, P. Mastromarino, R. Sessa   +3 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source