Results 131 to 140 of about 21,136 (238)

Promise to Practice: Reimagining Artificial Intelligence for Equitable Global Health Impact. [PDF]

open access: yesAnn Glob Health
Patel S   +15 more
europepmc   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

ProMED-mail: Background and Purpose

open access: yesEmerging Infectious Diseases, 2001
Jack Woodall, Charles H. Calisher
doaj   +1 more source

Human Pulmonary Dirofilariasis,
North Queensland, Australia, 2023<sup>1</sup>. [PDF]

open access: yesEmerg Infect Dis
Murray K   +7 more
europepmc   +1 more source

Corynoxine Inhibits Tumor Growth via Targeting NQO1 and Modulating the PTPA–NQO1/PP2A Switch to Activate PP2A

open access: yesAdvanced Science, EarlyView.
Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou   +6 more
wiley   +1 more source

Institutional Review Boards: Developing Countries Consideration

open access: yesEmerging Infectious Diseases, 2001
Jean William Pape
doaj   +1 more source

Home - About - Disclaimer - Privacy