Results 61 to 70 of about 21,663,268 (290)

Implementation of Artificial Intelligence in Food Science, Food Quality, and Consumer Preference Assessment

Foods, 2022
In recent years, new and emerging digital technologies applied to food science have been gaining attention and increased interest from researchers and the food/beverage industries [...]
Sigfredo Fuentes
doaj   +1 more source

Where are human subjects in Big Data research? The emerging ethics divide

Big Data & Society, 2016
There are growing discontinuities between the research practices of data science and established tools of research ethics regulation. Some of the core commitments of existing research ethics regulations, such as the distinction between research and ...
Jacob Metcalf, K. Crawford
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A clinical review of inhalation anesthesia with sevoflurane: from early research to emerging topics

Journal of Anesthesia, 2017
A large number of studies during the past two decades have demonstrated the efficacy and safety of sevoflurane across patient populations. Clinical researchers have also investigated the effects of sevoflurane, its hemodynamic characteristics, its ...
J. Brioni, Shane Varughese, R. Ahmed, B. Bein   +3 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Predictive value of self-prioritized mobility factors on gait speed and life space in older nigerians: A cross-sectional study

Archives of Gerontology and Geriatrics Plus
Background and Objectives: Eighty-two cognitive, environmental, financial, personal, physical, psychological, and social factors significantly influence mobility decline following hospital discharge.
Divine Esohe Eghomwanre, Freeman Ojeikere Ahonsi, Isreal Adandom, Tyler Sun, Daniel Rayner, Francis Kolawole, Henrietta Fawole, Soroush Shirazi, Michael Kalu   +8 more
doaj   +1 more source

The Pearl River Declaration: a timely call for enhancing health security through fostering a regional one health collaboration in the Asia-Pacific

Globalization and Health, 2020
The Second International Symposium on One Health Research (ISOHR) was held in Guangzhou city, China on 23–24 November 2019. A transdisciplinary collaborative approach, One Health (OH), was the central theme of the symposium which brought together more ...
Noore Alam, Cordia Chu, Qianlin Li, Allison Crook, Maxine Whittaker, Tjandra Aditama, Elena Schak, Dicky Budiman, Bonnie Barber, Jiahai Lu   +9 more
doaj   +1 more source