Results 71 to 80 of about 3,868,080 (298)

Predictive value of self-prioritized mobility factors on gait speed and life space in older nigerians: A cross-sectional study

Archives of Gerontology and Geriatrics Plus
Background and Objectives: Eighty-two cognitive, environmental, financial, personal, physical, psychological, and social factors significantly influence mobility decline following hospital discharge.
Divine Esohe Eghomwanre, Freeman Ojeikere Ahonsi, Isreal Adandom, Tyler Sun, Daniel Rayner, Francis Kolawole, Henrietta Fawole, Soroush Shirazi, Michael Kalu   +8 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Emergence in design science research

, 2020
Designing artifacts is a pivotal activity in Information Systems (IS) research. Beside the development process, the evaluation of artifacts is important as it allows the application of scientific methodologies to generate and accumulate knowledge. Commonly, the evaluation of an artifact is conducted in terms of the artifacts usefulness, utility or ...
Klesel, Michael, Henseler, Jörg
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Opening a can of worms : consenting partners in aged care

, 2015
With Consumer Directed Care (CDC) on the horizon and a wave of baby boomers who are ageing, aged care providers need to be aware of and respect the desires and requirements of future ‘consumers’. In contrast with current provider arrangements, funding is
Jones, Tiffany, Rahn, Alison (R19578), Lykins, Amy, Bennett, Cary   +3 more
core  

Enhancing mental health research capacity: emerging voices from the National Institute of Mental Health (NIMH) global hubs

International Journal of Mental Health Systems, 2019
Background Emerging researchers in low- and middle-income countries (LMIC) face many barriers, including inadequacies in funding, international exposure and mentorship.
Andrea Tenório Correia da Silva, Charlotte Hanlon, Ezra Susser, Graciela Rojas, Heloísa Garcia Claro, Julieta Quayle, Kassahun Habtamu, María Soledad Burrone, Maria Tavares Cavalcanti, Mona Sharma, Marguerite Schneider, Ramesh Prasad Adhikari, Tanya van de Water, Yasmin Mohammed, Anna E. Ordóñez, Soraya Seedat   +15 more
doaj   +1 more source

Education research in emergency medicine [PDF]

Internal and Emergency Medicine, 2016
Articles in the medical literature on the pedagogy of medical education are a relatively new phenomenon. While we have been interested in what to teach, few academic physicians have spent time studying how to teach, or assess the effectiveness of that teaching.
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source