Results 91 to 100 of about 1,816,741 (301)
Here Comes the Sunburst: Measuring and Visualizing Scholarly Impact [PDF]
Our ARL institution partnered with a new service (PlumX) to track, measure, and visualize faculty scholarly impact. In a pilot project, both traditional and emerging measures of scholarly impact were collected for 32 researchers.
Barnett, John H, Chan, Jennifer
core
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Background Poor hand hygiene (HH) among health care workers (HCWs) in low-resource healthcare settings has continued to increase the spread of infectious diseases, including COVID-19.
Ezinne Chika Ekediegwu +10 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Seeing the human behind the research: Strengthening emerging African disability researchers
Background: A pre-conference workshop that investigated the experiences and needs of PhD candidates and early career researchers in disability studies in Africa was held as part of the proceedings of the African Network for Evidence to Action in ...
Michelle Botha, Chioma Ohajunwa
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
HLA-CSPIF panel on commercial off-the-shelf distributed simulation [PDF]
Commercial-off-the-shelf (COTS) simulation packages are widely used in many areas of industry. Several research groups are attempting to integrate distributed simulation principles and techniques with these packages to potentially give us COTS ...
Gan, PB +3 more
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The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Use of Research Evidence: Social Services Portfolio [PDF]
The William T. Grant Foundation intends that the emerging research evidence from its Use of Research Evidence (URE) portfolio be useful to those engaged in these (and other) diverse efforts.
Susan Maciolek
core

