Results 171 to 180 of about 1,792,929 (311)

Emerging Technologies for Exploring the Cellular Mechanisms in Vascular Diseases. [PDF]

Int J Mol Sci
Sahu D, Ganguly T, Mann A, Gupta Y, Nynatten LRV, Fraser DD.   +5 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Neonatal supraventricular tachycardia: current diagnostic approaches and emerging technologies. [PDF]

Front Pediatr
Qi J, Yu R, Wang X.
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Host modulation therapy in periodontitis: from established therapies to emerging technologies. [PDF]

Front Immunol
Phanrungsuwan A, Huang J, Dharmaraj N, Cobos Perez A, Veiseh O, Young S, Lee CT.   +6 more
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Sugarcane Breeding in the Genomic Era: Integrative Strategies and Emerging Technologies. [PDF]

Plants (Basel)
Srithawong S, Fang W, Jing Y, Pholtaisong J, Li D, Khumla N, Sakuanrungsirikul S, Li M.   +7 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Editorial: Bioactivity and health benefits of bee products: emerging technologies and consumer insights. [PDF]

Front Nutr
Aquino JS, Valverde S, Pimentel TC.
europepmc   +1 more source

Emerging technologies for learning (volume 2) [PDF]

, 2007
Bryant, Lee, Downes, Stephen, Dumbleton, Tim, Facer, Keri, Ley, David, Prensky, Marc, Twist, Jo   +6 more
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