Emergomycosis (Emergomyces Africanus) in Advanced HIV Disease [PDF]
Dermatopathology (Basel, Switzerland), 2019 In 2013, a novel thermally dimorphic fungal pathogen was described to cause disseminated disease among persons living with advanced HIV/AIDS in South Africa.
Wayne Grayson, Nelesh P Govender
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Emergomyces Africanus: The Mimicking Fungus [PDF]
Dermatopathology (Basel, Switzerland), 2019 A 31-year-old HIV-seropositive woman from Durban, KwaZulu-Natal, South Africa, presented with a 3-month history of widespread umbilicated and ulcerated skin papules, plaques, and nodules.
Nelesh P Govender +2 more
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Morphological and Pathogenic Investigation of the Emerging Fungal Threat Emergomyces Africanus. [PDF]
Microbiology SpectrumEmergomyces africanus is a highly fatal fungal pathogen affecting individuals with advanced HIV disease. Molecular patterns and ultrastructural aspects of E. africanus are unknown, and pathogenic models have not been investigated in detail.
Leonardo Nimrichter +2 more
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Extracellular Vesicles of Emergomyces Africanus Modulate Host Immune Responses and Reflect Metabolic Adaptations to Nutrient Availability. [PDF]
Infection and ImmunityEmergomyces africanus is a thermal dimorphic fungus and a leading cause of emergomycosis, a neglected infection primarily affecting immunocompromised individuals. Despite its clinical relevance, little is known about how E.
Susana Frases +2 more
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Tools for Genetic Manipulation of the Endemic Fungal Pathogen Emergomyces Africanus and Application of a Fluorescent Reporter Strain in Infection Models. [PDF]
MSphereEmergomyces africanus is a thermally dimorphic fungal pathogen endemic to Southern Africa, which can cause fatal systemic infections in persons with advanced HIV disease. Its mechanisms of pathogenesis are not well understood.
Nelesh P Govender +2 more
exaly +9 more sources
Molecular Detection of Airborne Emergomyces Africanus, a Thermally Dimorphic Fungal Pathogen, in Cape Town, South Africa [PDF]
PLoS Neglected Tropical Diseases, 2018 Emergomyces africanus is a thermally dimorphic fungus that causes a systemic mycosis in immunocompromised persons in South Africa. Infection is presumed to follow inhalation of airborne propagules.
Chris Kenyon +2 more
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Uncovering the Potential Virulence Factors of Emerging Pathogens Using AI/ML-Based Tools: A Case Study in Emergomyces Africanus [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundWe are currently in the era of artificial intelligence (AI), which has become deeply embedded across nearly all scientific disciplines. Harnessing this revolutionary technology to predict virulence factors of emerging pathogens can improve our ...
Hibah M Albasri, Areej A Alhhazmi
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Paradoxical Worsening of Emergomyces Africanus Infection in an HIV-Infected Male on Itraconazole and Antiretroviral Therapy [PDF]
PLoS Neglected Tropical Diseases, 2018 1 Department of Medicine, University of Cape Town, Cape Town, Western Cape, South Africa, 2 Department of Dermatology, University of Cape Town, Cape Town, Western Cape, South Africa, 3 Department of Anatomical Pathology, National Health Laboratory ...
Nelesh P Govender +2 more
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Emergomyces africanus in Soil, South Africa [PDF]
Emerging Infectious Diseases, 2018 We detected Emergomyces africanus, a thermally dimorphic fungus that causes an HIV-associated systemic mycosis, by PCR in 18 (30%) of 60 soil samples from a wide range of habitats in South Africa. Direct and indirect culture techniques were unsuccessful.
Ilan S. Schwartz +9 more
doaj +8 more sources
In Vitro Manogepix Susceptibility Testing of South African Emergomyces Africanus, Emergomyces pasteurianus, and Blastomyces Emzantsi Clinical Isolates. [PDF]
Antimicrobial Agents and Chemotherapy, 2023 We performed in vitro antifungal susceptibility testing of manogepix against the yeast phase of 78 Emergomyces africanus, 2 Emergomyces pasteurianus, and 5 Blastomyces emzantsi isolates using a reference broth microdilution method following Clinical and ...
Nelesh P Govender +2 more
exaly +5 more sources