Results 11 to 20 of about 28,155 (204)

Chemotherapy-Induced Nausea and Vomiting in Early Breast Cancer Patients Receiving Adjuvant Chemotherapy With Fluorouracil, Epirubicin, Cyclophosphamide Followed by Docetaxel Versus an Anthracycline-Free Regimen With Docetaxel, Cyclophosphamide-Results From a Randomized Clinical Trial. [PDF]

Int J Cancer
Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Hörner M, Schäffler H, Häberle L, Goossens C, Pfister K, Leinert E, Veselinovic K, Brucker SY, Köhler U, Heinrich G, Schneeweiss A, Beckmann MW, Fasching PA, Janni W, Rack B, Heublein S, Ziegler P.   +16 more
europepmc   +2 more sources

Involvement of 5-Serotonin and Substance p Pathways in Dichroa Alkali Salt-Induced Acute Pica in Rats

Frontiers in Pharmacology, 2021
Dichroa alkali salt (DAS) is the active ingredient of Changshan, a traditional Chinese antimalarial medicine. However, owing to its vomiting side effects, its clinical use is limited. Recently, DAS-induced vomiting has attracted broad attention; however,
Lina Ma, Lina Ma, Sidi Li, Jian Li, Guangping Zhang, Hongping Hou, Zuguang Ye   +6 more
doaj   +1 more source

Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice

Biology, 2021
Treatment with PAN-PDE4 inhibitors has been shown to produce hypothermia in multiple species. Given the growing body of evidence that links nausea and emesis to disturbances in thermoregulation in mammals, we explored PDE4 inhibitor-induced hypothermia ...
Abigail Boyd, Ileana V. Aragon, Justin Rich, Will McDonough, Marianna Oditt, Daniel Irelan, Edward Fiedler, Lina Abou Saleh, Wito Richter   +8 more
doaj   +1 more source

Anti-emetic Action of the Brain-Penetrating New Ghrelin Agonist, HM01, Alone and in Combination With the 5-HT3 Antagonist, Palonosetron and With the NK1 Antagonist, Netupitant, Against Cisplatin- and Motion-Induced Emesis in Suncus murinus (House Musk Shrew)

Frontiers in Pharmacology, 2018
Ghrelin has well-known activity to stimulate appetite and weight gain. Evidence suggests that ghrelin may also have effects in reducing chemotherapy-induced emesis via growth hormone secretagogue receptors (GHS-R1A) in the brain. However, it is not known
John A. Rudd, John A. Rudd, Sze W. Chan, Man P. Ngan, Longlong Tu, Zengbing Lu, Claudio Giuliano, Emanuela Lovati, Claudio Pietra   +8 more
doaj   +1 more source

Tic Reduction Following Heat-Induced Dehydration in Gilles de la Tourette Syndrome (TS)

Biology and Life Sciences Forum, 2022
A 24-year-old man with of Gilles de la Tourette (TS) syndrome experienced a marked remission of 2 years after heat-induced dehydration. Further investigation of the effects of heat and dehydration on TS may be useful.
Ashley B. Durbin, Matthew R. Rodgers, James Robert Brašić   +2 more
doaj   +1 more source

Action of Cyclooxygenase Inhibitors and a Leukotriene Biosynthesis Inhibitor on Cisplatin-Induced Acute and Delayed Emesis in the Ferret

Journal of Pharmacological Sciences, 2007
Cisplatin at 5 mg/kg, i.p. induced an acute (day 1) and delayed (days 2 and 3) emetic response in the ferret that was used to investigate the anti-emetic activity of the non-selective cyclooxygenase inhibitor indomethacin (3 – 30 mg/kg, i.p., three times
Tasia S.W. Sam, Man P. Smith, Denis Riendeau, Annette Robichaud, John A. Smith   +4 more
doaj   +1 more source

Type II achalasia unmasked by EndoFLIP and high-resolution manometry in a child with eosinophilic esophagitis. [PDF]

JPGN Rep
ABSTRACT Eosinophilic esophagitis (EoE) is a chronic immune‐mediated disease characterized by esophageal dysfunction and eosinophilic inflammation. Persistent dysphagia despite histologic remission should prompt evaluation for alternative etiologies. A 10‐year‐old male with asthma and eczema presented with progressive solid food dysphagia, daily non ...
Jaoudeh RARA, Garza JM, Rajendra C.
europepmc   +2 more sources

Functional Emesis

Journal of Gastrointestinal and Liver Diseases, 2019
Background: Emesis is an essential survival response, because consumption of food is a key element in the survival behavior and the act of feeding can expose the majority of internal organs to toxins, altered food, viruses, bacteria or fungi. The relationship between visceral or vestibular stimuli and the anatomical structures of the brain-gut axis ...
Popa, Stefan Lucian, Chiarioni, Giuseppe, David, Liliana, Golea, George Ionut, Dumitrascu, Dan Lucian   +4 more
openaire   +4 more sources

Urocystitis, pyelonephritis, renal papillary necrosis and chronic tubulointerstitial disease causing chronic renal insufficiency in a Siberian tiger (Panthera tigris altaica): a case report

Veterinární Medicína, 2018
The present case report describes a case of chronic renal failure characterised by renal medullary fibrosis and renal papillary necrosis in a male Siberian tiger (Panthera tigris altaica).
S.W. Lee, A.K. Elfadl, M.J. Chung, H.M. Arif Ullah, D.K. Yuh, S.H. Lee, K.S. Jeong, J.K. Park   +7 more
doaj   +1 more source

Cannabis, a Miracle Drug with Polyvalent Therapeutic Utility: Preclinical and Clinical-Based Evidence

Medical Cannabis and Cannabinoids, 2021
Cannabis sativa L. is an annual herbaceous dioecious plant which was first cultivated by agricultural human societies in Asia. Over the period of time, various parts of the plant like leaf, flower, and seed were used for recreational as well as ...
Rishabh Verma, Farazul Hoda, Mawrah Arshad, Asif Iqubal, Ali Nasir Siddiqui, Mohammad Ahmed Khan, Syed Ehtaishamul Haque, Mohd Akhtar, Abul Kalam Najmi   +8 more
doaj   +1 more source